ArticleAnnals of medicine and surgery (2012)2025
Pulmonary syphilis mimicking lung metastasis: a case report.
Article in Annals of medicine and surgery (2012), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Abstract
Introduction: Syphilis, due to Case report: A 54-year-old HIV-positive man was referred for multiple subpleural bilateral lung nodules without mediastinal lymphadenopathy on a computedtomography (CT) of the chest carried out for symptoms combining dry cough, sweats, night chills, right basi-thoracic pain, and a weight loss of 4 kg in a few weeks. His medical history revealed pneumocystis infection and secondary syphilis, occurring 10 and 8 years ago, respectively. His regular partner did not have any symptoms and deranged biological analysis. The clinical examination was normal except for a maculopapular rash on the back, hands, and forearms. A skin biopsy was performed which revealed the presence of Discussion: Pulmonary involvement in secondary syphilis is very rare in comparison to congenital or tertiary syphilis. However coinfection with HIV increases the frequency of atypical presentation of the disease. Despite the presence of usual clinical criteria for the diagnosis of pulmonary involvement and an HIV disease controlled with antiretroviral treatment, a CT-guided fine needle aspiration of a nodule was done to rule out neoplastic disease or other infection. Conclusion: With the rise of syphilis cases, physicians have to be aware of non-specific clinical presentation of the disease in particular in case of coinfection with HIV.
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