Evidence map›Paper›PMID 41181428›Full record

ArticleAnnals of medicine and surgery (2012)2025

Raised a eunuch: a case report of testicular loss without androgen replacement in a pre-pubescent boy.

Jamie D Agapoff, Richard J Wassersug, Thomas W Johnson

Abstract readCase Reports
In one paragraph

Article in Annals of medicine and surgery (2012), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jamie D AgapoffDepartment of Psychiatry, John A. Burns School of Medicine, University of Hawai'i at Manoa, Honolulu, HI, USA.ORCID https://orcid.org/0000-0002-6026-6463
Richard J WassersugDepartment of Cellular and Physiological Sciences, University of British Columbia, Vancouver, Canada.ORCID https://orcid.org/0000-0001-7028-7615
Thomas W JohnsonDepartment of Anthropology (Emeritus), California State University, Chico, USA.ORCID https://orcid.org/0000-0002-2613-9217

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction & Importance: Bilateral testicular torsion with testicular loss is a rare condition in prepubertal youth. This case represents one of the only documented cases of a modern, pre-pubertal youth raised as a eunuch through adolescence. Case Presentation: This is a case of a pre-pubertal boy (Z) who suffered bilateral testicular torsion and gonadal loss who was raised as a eunuch through adolescence. Clinical Discussion: Throughout his adolescence, Z demonstrated no deficits in psychosocial functioning, and displayed no intellectual or learning deficits. Compared to his peers and younger brother, Z was less interested in physical and competitive activities, preferring more supportive, pro-social behaviors, like caring for children. Conclusion: In this case, hormonal deprivation and delayed puberty did not appear to impact neurodevelopmental processes or psychosocial development. This case has potential issues for other areas of healthcare where concerns have arisen around long-term pubertal suppression.

Indexed as

case reporteunuchorchiectomypediatricstesticular torsionurology

Identifiers

PMID41181428
PMCPMC12577921

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.