ArticleJournal of inflammation research2025
The Relationship Between IL-6 and IL-10 Expression Levels and the Prognosis in B-Cell Non-Hodgkin Lymphoma Patients Treated with R-CHOP.
Article in Journal of inflammation research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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10 authors.
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Abstract
Purpose: To explore the relationship between the expression of IL-6 and IL-10 in the blood of B-cell non-Hodgkin lymphoma (B-NHL) patients and their survival time and adverse reactions. Methods: The study collected and analyzed blood samples from 488 patients with B-NHL treated with rituximab (94 serum samples, 394 plasma samples) as well as plasma samples from 202 healthy subjects, along with relevant clinical information. Expression levels of IL-6 and IL-10 in the blood were measured using enzyme-linked immunosorbent assay (ELISA). Results: The expression of IL-6 in the plasma of B-NHL patients was significantly higher than those in healthy subjects ( Conclusion: The expression of IL-6 and IL-10 in the blood can serve as important biomarkers for predicting the prognosis of rituximab in patients with B-NHL.
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