Evidence map›Paper›PMID 41181317›Full record

ArticleFrontiers in cellular and infection microbiology2025

Rapid detection of Golgi protein 73 by MAGLUMI chemiluminescent immunoassay and the clinical value to liver fibrosis/cirrhosis patients with chronic liver disease.

Lu Wang, Wen Dai, Jie Rao, Yichen Wang, Kun Liu, Xing Li, Hua Wang, Jiahuan Ye, Zhonggang Fang, Xin Zheng

Abstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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0 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Lu Wang *Department of Infectious Diseases, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Wen Dai *Department of Clinical Laboratory, Institute of Translational Medicine, Renmin Hospital of Wuhan University, Wuhan, Hubei, China.
Jie Rao *Research & Development Department, Shenzhen New Industries Biomedical Engineering, Shenzhen, Guangdong, China.
Yichen WangResearch & Development Department, Shenzhen New Industries Biomedical Engineering, Shenzhen, Guangdong, China.
Kun LiuResearch & Development Department, Shenzhen New Industries Biomedical Engineering, Shenzhen, Guangdong, China.
Xing LiResearch & Development Department, Shenzhen New Industries Biomedical Engineering, Shenzhen, Guangdong, China.
Hua Wang *Department of Infectious Diseases, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Jiahuan Ye *Department of Infectious Diseases, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Zhonggang FangResearch & Development Department, Shenzhen New Industries Biomedical Engineering, Shenzhen, Guangdong, China.
Xin ZhengDepartment of Infectious Diseases, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To investigate the diagnostic value of MAGLUMI chemiluminescent immunoassay (CLIA) for detecting Golgi protein 73 (GP73) in patients with chronic liver disease. Methods: A total of 212 patients with chronic liver disease were selected as the research subjects. METAVIR pathological staging was performed according to LSM values, and GP73 levels were detected by CLIA. Spearman analysis was used to analyze the correlation between GP73, LSM and METAVIR staging. The diagnostic efficacy of GP73 was analyzed using the ROC curve based on METAVIR staging. Results: The enrolled patients included 37 patients in F0/F1, 80 patients in F2, 61 patients in F3, and 34 patients in F4. There were significant differences in GP73 levels in each stage ( Conclusion: GP73 detected by CLIA was positively correlated with liver fibrosis stage and LSM, and had important clinical value in diagnosis of liver fibrosis and cirrhosis in patients with chronic liver disease.

Indexed as

ImmunoassayLiver CirrhosisLiver DiseasesLuminescent MeasurementsMembrane ProteinsAdultAgedAged, 80 and overBiomarkersChronic DiseaseFemaleHumansMaleMiddle AgedTime FactorsYoung AdultBiomarkersGOLM1 protein, humanMembrane ProteinsdiagnosisGP73immunoassayliver fibrosisperformance evaluation

Identifiers

PMID41181317
PMCPMC12571778

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.