ArticleJournal of anaesthesiology, clinical pharmacology
Comparison of two concentrations (0.125% and 0.25%) of bupivacaine for ultrasound guided sacral erector spinae block in paediatric patients undergoing hypospadias repair: A double blind randomised trial.
Article in Journal of anaesthesiology, clinical pharmacology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed.
- Ultrasound-guided erector spinae plane block versus serratus anterior plane block for analgesia and respiratory function in patients with multiple rib fractures: a large-sample, single-center, randomized, double-blind, controlled trial.Frontiers in medicine · 2026Trial
- Comparison of sacral erector spinae plane block and caudal epidural block for postoperative analgesia in pediatric hypospadias surgery: a prospective observational study.Perioperative medicine (London, England) · 2026Article
- The Sacral Erector Spinae Plane Block: A Narrative Review.Pain and therapy · 2026Review
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background and Aims: The volume and concentration of local anaesthetic are particularly importance for the success of a block in providing analgesia. To improve safety, the goal should be the minimum dose of local anaesthetic capable of providing maximum effectiveness. Interfascial plane blocks are considered volume blocks, and a higher volume of local anaesthetic needs to be injected into the fascial plane to achieve the desired effect. Reducing the local anaesthetic concentration may limit the total dose administered without changing the volume injected. Material and Methods: Sixty children aged 8-12 years undergoing hypospadias repair were included in the study. After the induction of general anaesthesia, Group I (n = 30) was given an ultrasound-guided sacral erector spinae block with 1 ml/kg of 0.125% bupivacaine, and Group II (n = 30) received the same block with 1 ml/kg of 0.25% bupivacaine. Postoperatively, when the visual analogue scale (VAS) score was ≥ 4, rescue analgesia was administered using intravenous paracetamol at 15 mg/kg. The primary objective was to compare the time to the first paracetamol rescue. Secondary objectives included intraoperative hemodynamic parameters, additional fentanyl consumption, postoperative visual analogue scores, and total analgesic consumption (paracetamol and ibuprofen) within 24 h. Results: The mean time to the first paracetamol rescue was 20.0 h (standard deviation [SD]: 3) h in Group I and 22.5 h (SD: 3) h in Group II ( Conclusions: Bupivacaine 0.125% is as effective as 0.25% bupivacaine in terms of the time to first paracetamol rescue for sacral erector spinae block in paediatric patients undergoing hypospadias repair.
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