ArticleJournal of anaesthesiology, clinical pharmacology
Comparison of dexmedetomidine and cold thermotherapy for the relief of pain on propofol injection: A randomized controlled trial.
Article in Journal of anaesthesiology, clinical pharmacology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background and Aims: Pain on propofol injection (POPI) leads to intense patient discomfort during the induction of anesthesia. This study aimed to compare the efficacy of intravenous dexmedetomidine and topical cold thermotherapy in the relief of POPI. Material and Methods: This randomized controlled trial was conducted on 274 adults undergoing elective surgery under general anesthesia. Patients received dexmedetomidine (0.25 µg/kg) following the application of a tourniquet proximal to the intravenous cannulation site for 30 s (Group D, n = 137), or an ice pack gel (260 mm × 125 mm) was applied proximal to the site of the cannula for 1 min (Group T, n = 137). The primary objective was to assess and compare the incidence and severity of POPI using the McCrirrick and Hunter Scale. The secondary objectives included the comparison of the induction dose of propofol and the hemodynamics (heart rate, blood pressure) at induction, along with the assessment of the presence of discomfort following ice gel pack application. Results: The incidence of pain was greater in Group D as compared to Group T (54.74% v/s 29.17%, Conclusion: The application of ice gel pack thermotherapy is associated with a significant reduction in POPI as compared to pre-treatment with dexmedetomidine (0.25 µg/kg), with no significant adverse effects.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.