Evidence map›Paper›PMID 41181218›Full record

ArticleEpigenetics reports2025

Vafidemstat: a lysine-specific demethylase 1A inhibitor that shows promise for treating neuropsychiatric disorders.

Jacob Peedicayil, Dennis R Grayson

Abstract read
In one paragraph

Article in Epigenetics reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Jacob PeedicayilDepartment of Pharmacology and Clinical Pharmacology, Christian Medical College, Vellore, India.ORCID 0000-0001-8874-0289
Dennis R GraysonDepartment of Psychiatry, Center for Alcohol Research in Epigenetics, The Psychiatric Institute, College of Medicine, University of Illinois, Chicago, IL, USA.ORCID 0000-0002-4544-5869

Funding

Pilot Project Program P50AA022538 · NIAAA · UNIVERSITY OF ILLINOIS AT CHICAGO · PI SUBHASH C. PANDEY · 2015 to 2026
$21.3M
NIAAA NIH HHS P50 AA022538
6 · The paper itself

Abstract

The enzyme KDM1A encoded by

Indexed as

KDM1Alysine-specific demethylase 1neuropsychiatric disordervafidemstat

Identifiers

PMID41181218
PMCPMC12577760

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.