Evidence map›Paper›PMID 41181150›Full record

ReviewFrontiers in immunology2025

Periodontopathic bacteria in rheumatoid arthritis pathogenesis: bridging clinical associations to molecular mechanisms.

Xiaojing Guo, Siwei Wang, Jiuli Ding, Weiwei Liu, Jiaqi Xu, Mutian Wang, Hongyuan Sun, Yuening Ma, Wei Liu, Lei Zhang and 1 more

Abstract readReview
In one paragraph

Review in Frontiers in immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Molecular Detection ofDiagnostics (Basel, Switzerland) · 2026
    Article
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Xiaojing Guo *Department of Infectious Diseases, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Siwei Wang *Department of Infectious Diseases, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Jiuli Ding *Graduate School, Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Weiwei LiuDepartment of Infectious Diseases, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Jiaqi XuDepartment of Infectious Diseases, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Mutian WangDepartment of Respiratory Medicine, Shanxi Provincial Academy of Traditional Chinese Medicine, Shanxi, China.
Hongyuan SunDepartment of Infectious Diseases, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Yuening MaDepartment of Infectious Diseases, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Wei LiuDepartment of Infectious Diseases, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Lei ZhangOffice of the President,Tianjin Academy of Traditional Chinese Medicine Affiliated Hospital, Tianjin, China.
Min LiuDepartment of Infectious Diseases, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Periodontitis (PD) is a chronic inflammatory disease linked to microbial dysbiosis, while rheumatoid arthritis (RA) is an autoimmune disorder characterized by anti-citrullinated protein antibodies (ACPA). Despite their distinct etiologies, a clinical and serological association between PD and RA has been observed. Oral microorganisms, especially

Indexed as

Arthritis, RheumatoidPeriodontitisPorphyromonas gingivalisAnimalsDisease SusceptibilityDysbiosisHumansMicrobiotacitrullinated antigensoral pathogensperiodontitisporphyromonas gingivalisrheumatoid arthritis

Identifiers

PMID41181150
PMCPMC12575381

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.