Evidence map›Paper›PMID 41181110›Full record

ArticleFrontiers in immunology2025

Caraugh Jane Albany, Daniela Mastronicola, Momchil Popov, Wladislaw Stroukov, Anthony S Wierzbicki, Rocio Teresa Martinez-Nunez, Giovanna Lombardi, Cristiano Scottà

Abstract read
In one paragraph

Article in Frontiers in immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Caraugh Jane Albany *'Peter Gorer' Department of Immunobiology, King's College, London, United Kingdom.
Daniela Mastronicola *'Peter Gorer' Department of Immunobiology, King's College, London, United Kingdom.
Momchil Popov'Peter Gorer' Department of Immunobiology, King's College, London, United Kingdom.
Wladislaw Stroukov'Peter Gorer' Department of Immunobiology, King's College, London, United Kingdom.
Anthony S WierzbickiDepartment of Metabolic Medicine/Chemical Pathology Guy's & St Thomas' Hospitals, London, United Kingdom.
Rocio Teresa Martinez-NunezDepartment of Infectious Diseases, King's College, London, United Kingdom.
Giovanna Lombardi'Peter Gorer' Department of Immunobiology, King's College, London, United Kingdom.
Cristiano Scottà'Peter Gorer' Department of Immunobiology, King's College, London, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lipid-driven inflammation contributes to the development of atherosclerosis, and regulatory T cells (Tregs) have been proposed to influence macrophage responses to lipid stress. While adoptive Treg transfer has been shown to be safe in clinical studies, the mechanisms by which Tregs modulate macrophage lipid handling remain incompletely understood. In this study, we investigated the effects of

Indexed as

AryldialkylphosphataseCholesterolCyclic AMPGap JunctionsLipoproteins, LDLMacrophagesT-Lymphocytes, RegulatoryCells, CulturedCoculture TechniquesHumansAryldialkylphosphataseCholesterolCyclic AMPLipoproteins, LDLoxidized low density lipoproteinPON1 protein, humanatherosclerosischolesterolmacrophagesparaxonase-1regulatory T (Treg) cells

Identifiers

PMID41181110
PMCPMC12571657

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.