Evidence map›Paper›PMID 41180972›Full record

ArticleThe archives of bone and joint surgery2025

Promising Results of Total Knee Arthroplasty in Patients with Severe Varus Deformity with High Constrained Prosthesis: A Prospective Study.

Mahmoud Jabalameli, Alireza Askari, Hooman Yahyazadeh, Abolfazl Bagherifard, Mohammad Jabalameli, Mohammadreza Dolikhani, Mehrdad Sadighi

Abstract read
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Article in The archives of bone and joint surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Mahmoud JabalameliBone and Joint Reconstruction Research Center, Shafa Orthopedic Hospital, Iran University of Medical Sciences, Tehran, Iran.
Alireza AskariBone and Joint Reconstruction Research Center, Shafa Orthopedic Hospital, Iran University of Medical Sciences, Tehran, Iran.
Hooman YahyazadehBone and Joint Reconstruction Research Center, Shafa Orthopedic Hospital, Iran University of Medical Sciences, Tehran, Iran.
Abolfazl BagherifardBone and Joint Reconstruction Research Center, Shafa Orthopedic Hospital, Iran University of Medical Sciences, Tehran, Iran.
Mohammad JabalameliBone and Joint Reconstruction Research Center, Shafa Orthopedic Hospital, Iran University of Medical Sciences, Tehran, Iran.
Mohammadreza DolikhaniBone and Joint Reconstruction Research Center, Shafa Orthopedic Hospital, Iran University of Medical Sciences, Tehran, Iran.
Mehrdad SadighiBone and Joint Reconstruction Research Center, Shafa Orthopedic Hospital, Iran University of Medical Sciences, Tehran, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: The existing literature does not provide a clear definition of the outcomes of total knee arthroplasty (TKA) and prosthesis constraint in patients with severe varus deformity. In this study, for the first time, we evaluated the outcomes of TKA and the relationship between prosthesis constraint and these outcomes in patients with severe varus deformity (>30 degrees). Methods: This prospective cohort study was conducted on 41 patients (54 knees) with varus deformity greater than 30 degrees who underwent TKA between April 2013 and April 2019. The patients were divided into two groups based on the type of prosthesis (high constraint and low constraint). Surgical outcomes were evaluated using the Knee Society Score (KSS), Oxford Knee Score (OKS), range of motion (ROM), and postoperative complications. Results: High-constrained prostheses (HCP) and low-constrained prostheses (LCP) were used in 44 and 10 knees, respectively. The mean follow-up duration was 77.11 ± 6.55 months. The mean KSS, KSS function, OKS, and ROM significantly improved after surgery compared to preoperative values (P<0.05). The mean improvement in the KSS function score after surgery was significantly higher in patients with HCP compared to those with LCP (p = 0.021). No significant differences were observed for the other variables. No cases required revision. Conclusion: This prospective non-randomized study, conducted on 41 patients (54 knees) with severe varus deformity (>30º) who underwent total knee arthroplasty (TKA), demonstrated that the mean improvement in the Knee Society Score (KSS) function score after surgery was greater for high-constrained prostheses (HCP, N = 44) compared to low-constrained prostheses (LCP, N = 10). The HCP group included 40 Legacy Constrained Condylar Knees (LCCK) and four hinged knee prostheses, while the LCP group included posterior-stabilizing (PS) prostheses. The mean follow-up duration was 6.5 years. Given the small sample size, randomized clinical trials are needed to validate our preliminary findings.

Indexed as

Constrained prosthesisFunctional scoreKnee osteoarthritisSevere varusTotal knee arthroplasty

Identifiers

PMID41180972
PMCPMC12576335

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