Evidence map›Paper›PMID 41180934›Full record

ArticleInternational journal of transgender health2025

Multi-level correlates of oral pre-exposure prophylaxis discontinuation among English and Spanish-speaking transgender women of color in New York City: The TURNNT cohort study.

Alexander Furuya, Asa Radix, Krish J Bhatt, Adam Whalen, Su Hyun Park, Jessica Contreras, Roberta Scheinmann, Cristina Herrera, Kim Watson, Denton Callandar and 4 more

Abstract read
In one paragraph

Article in International journal of transgender health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Alexander FuruyaDepartment of Epidemiology, Columbia University Mailman School of Public Health, New York, NY, USA.ORCID https://orcid.org/0009-0008-4596-9014
Asa RadixDepartment of Epidemiology, Columbia University Mailman School of Public Health, New York, NY, USA.
Krish J BhattDepartment of Epidemiology, Columbia University Mailman School of Public Health, New York, NY, USA.
Adam WhalenDepartment of Epidemiology, Columbia University Mailman School of Public Health, New York, NY, USA.
Su Hyun ParkDepartment of Epidemiology, Columbia University Mailman School of Public Health, New York, NY, USA.
Jessica ContrerasDepartment of Epidemiology, Columbia University Mailman School of Public Health, New York, NY, USA.
Roberta ScheinmannDepartment of Epidemiology, Columbia University Mailman School of Public Health, New York, NY, USA.
Cristina HerreraTrans Latina Network, New York, New York, USA.
Kim WatsonCK Life, New York, New York, USA.
Denton CallandarDepartment of Epidemiology, Columbia University Mailman School of Public Health, New York, NY, USA.
John A SchneiderDepartment of Medicine, University of Chicago, Chicago, Illinois, USA.ORCID https://orcid.org/0009-0003-0553-3447
Sahnah LimCallen-Lorde Community Health Center, New York, New York, USA.ORCID https://orcid.org/0000-0001-7406-5235
Chau Trinh-ShevrinCallen-Lorde Community Health Center, New York, New York, USA.
Dustin T DuncanDepartment of Epidemiology, Columbia University Mailman School of Public Health, New York, NY, USA.ORCID https://orcid.org/0000-0001-8586-8711

Funding

Supplemental Training in Making Data FAIR and AI/ML ReadyT32ES007322 · NIEHS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Pam R Factor-Litvak, Allison Kupsco · 2000 to 2026
$12.1M
Global HIV Implementation Science Research Training Grant RenewalT32AI114398 · NIAID · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Yael R Hirsch-Moverman · 2014 to 2026
$4.1M
Medical Mistrust as a Barrier to COVID-19 and HIV Services Among Transgender Women of ColorR01MD013554 · NIMHD · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI DUNCAN, DUSTIN T · 2018 to 2022
$3.7M
NIAID NIH HHS T32 AI114398NIEHS NIH HHS T32 ES007322NIMHD NIH HHS R01 MD013554
6 · The paper itself

Abstract

Background: Transgender women of color in the US are disproportionately vulnerable to HIV risks. Pre-Exposure Prophylaxis (PrEP) has demonstrated effectiveness in preventing HIV transmission among transgender women of color. However, factors across multiple levels can hinder oral PrEP adherence. Methods: We analyzed the baseline data from The Trying to Understand Neighborhoods and Networks Among Transgender Women of Color (TURNNT) Cohort Study of women not living with HIV. We analyzed questionnaire responses to identify why participants stopped using PrEP and if they would consider taking it again. To identify multi-level determinants that were associated with PrEP discontinuation, we conducted bivariate analysis and created multivariable modified Poisson models comparing factors between former users and current users. Results: Among 140 transgender women of color included in this analysis, 44.3% were currently on PrEP, 25.0% were on formerly on the regimen, and 30.7% had never used it. Participants reported many reasons for discontinuing PrEP, notably, 22.9% reported being concerned about interactions with hormones. 60.0% reported that they were likely to take PrEP again in the future. Discontinuation was positively associated with history of sexual assault (Prevalence Ratio: 1.78; 95% CI: 1.01, 3.14) and negatively with having a primary care provider (PR: 0.43; 95% CI: 0.25, 0.73). Conclusion: Many factors can influence PrEP discontinuation among transgender women of color. A majority of those who discontinued PrEP were interested in restarting it again, indicating a potential for reengagement. We recommend a holistic approach to HIV prevention to reduce PrEP discontinuation.

Indexed as

HIVintersectionalityintervention scienceLGBTQ healthmultilevel determinantssocial determinants of health

Identifiers

PMID41180934
PMCPMC12573547

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.