Evidence map›Paper›PMID 41180851›Full record

ArticlePain reports2025

Clarifying the postsurgical persistent pain after laparoscopic cholecystectomy and the role of intravenous lidocaine.

Margarida Abreu-Pires, Carla Cavaleiro, Humberto Machado, Álvaro Moreira da Silva

Abstract read
In one paragraph

Article in Pain reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Margarida Abreu-PiresServiço de Anestesiologia, Centro Hospitalar Universitário de Santo António, Unidade Local de Saúde de Santo António, Porto, Portugal.ORCID https://orcid.org/0009-0001-1458-9915
Carla CavaleiroServiço de Anestesiologia, Centro Hospitalar Universitário de Santo António, Unidade Local de Saúde de Santo António, Porto, Portugal.
Humberto MachadoServiço de Anestesiologia, Centro Hospitalar Universitário de Santo António, Unidade Local de Saúde de Santo António, Porto, Portugal.
Álvaro Moreira da SilvaInstituto de Ciências Biomédicas Abel Salazar, Universidade do Porto, Porto, Portugal.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Persistent abdominal pain after laparoscopic cholecystectomy (PAPLC) incidence is estimated between 3% and 56%. Data concerning PAPLC intensity and its neuropathic characteristics is scarce, and the role of intravenous lidocaine on PAPLC is not clarified. Objectives: The authors aim to evaluate PAPLC prevalence, intensity, risk factors, and neuropathic pain (NP) characteristics. Intravenous lidocaine's impact on acute and persistent pain and opioid consumption was explored. Methods: In a 3-year follow-up, participants (n = 93) were enquired by telephone after informed consent. Sociodemographic characteristics, intraoperative and postoperative analgesia, acute pain control, preoperative chronic abdominal pain (PCAP), intensity (numeric pain scale score [NPSS]), and Results: A 15.05% prevalence of PAPLC was observed. About 57.1% of PAPLC patients reported moderate-to-severe pain. All PAPLC patients reported NP features. The intraoperative fentanyl dose ( Conclusion: This study's findings indicate a high PAPLC prevalence and a significant percentage of moderate-to-severe pain. Neuropathic pain characteristics should not be overlooked. The observed PAPLC risk factors follow the evidence. Intravenous lidocaine reduced the need for rescue opioid analgesia in the PACU and nonopioid analgesia in the postoperative period.

Indexed as

Chronic abdominal painIntravenous lidocaineLaparoscopic cholecystectomyPain classificationPersistent abdominal pain

Identifiers

PMID41180851
PMCPMC12577849

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.