ArticleOncology letters2026
Advanced dual primary male breast cancer and lung cancer: A case report and literature review.
Article in Oncology letters, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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8 authors.
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Abstract
The current report presents a unique case of advanced male invasive breast cancer coexisting with synchronous primary lung adenocarcinoma, a rare clinical manifestation. The case contributes to the limited literature on male breast cancer and its association with multiple primary malignancies. The patient, a 59-year-old man, presented with a large ulcerative mass in the left breast (14×10 cm) and ground-glass opacities with calcified nodules in the right lower lung lobe (14×14 mm). Imaging and pathology confirmed stage IIIB invasive ductal carcinoma of the breast [human epidermal growth factor receptor-2-positive, estrogen receptor-positive (80%) and progesterone receptor-positive (5%)] and minimally invasive lung adenocarcinoma. Treatment consisted of neoadjuvant chemotherapy (epirubicin + carboplatin + trastuzumab + pertuzumab), a modified radical mastectomy with latissimus dorsi flap reconstruction and a thoracoscopic lung wedge resection. The therapeutic approach resulted in partial remission of the breast cancer prior to surgery and a stable disease status in the lung, with no recurrence at the 1-year follow-up. This case underscores the importance of comprehensive, integrative strategies and long-term follow-up for managing rare, complex cancer cases.
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