Evidence map›Paper›PMID 41180802›Full record

ArticleJournal of the anus, rectum and colon2025

Prognostic Impact of C-reactive Protein-albumin-lymphocyte Index in Elderly Patients with Colorectal Cancer.

Yasunobu Kobayashi, Yasuhiro Takano, Saya Matsukida, Teruyuki Takishima, Hironori Kanno, Nobuyoshi Hanyu, Ken Eto

Abstract read
In one paragraph

Article in Journal of the anus, rectum and colon, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yasunobu KobayashiDepartment of Surgery, Tokyo General Hospital, Tokyo, Japan.
Yasuhiro TakanoDepartment of Surgery, The Jikei University School of Medicine, Tokyo, Japan.
Saya MatsukidaDepartment of Surgery, Tokyo General Hospital, Tokyo, Japan.
Teruyuki TakishimaDepartment of Surgery, Tokyo General Hospital, Tokyo, Japan.
Hironori KannoDepartment of Surgery, Tokyo General Hospital, Tokyo, Japan.
Nobuyoshi HanyuDepartment of Surgery, Tokyo General Hospital, Tokyo, Japan.
Ken EtoDepartment of Surgery, The Jikei University School of Medicine, Tokyo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: This study aimed to assess the prognostic impact of the C-reactive protein-albumin-lymphocyte index in older patients with colorectal cancer and to evaluate the superiority of this new system. Methods: Of the patients who received initial treatment for colorectal cancer at our hospital between 2014 and 2021 (n=269), older patients aged ≥65 years who had undergone curative resection for colorectal cancer during the study period were included. We retrospectively investigated the relationship between the preoperative C-reactive protein-albumin-lymphocyte index and overall and recurrence-free survival rates. Univariate and multivariate analyses were performed to identify the independent prognostic factors after curative resection in older patients with colorectal cancer. Results: One-hundred-seventy-eight patients underwent initial curative resection during the study period. The median survival times for patients with C-reactive protein-albumin-lymphocyte (CALLY) indices <1.2 and ≥1.2 were 42.6 and 68.3 months, respectively ( Conclusions: Our study suggests that the CALLY index is an independent prognostic factor in older patients with colorectal cancer and may facilitate multidisciplinary decision-making.

Indexed as

CALLY indexcolorectal cancerolder patientsprognostic factor

Identifiers

PMID41180802
PMCPMC12574810

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.