ReviewAnnals of medicine and surgery (2012)2025
Benzene and human health: a comprehensive review of carcinogenic risks, mechanisms, and preventive strategies.
Review in Annals of medicine and surgery (2012), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Industries widely utilize benzene in the production of plastics, resins, and fibers. It is also present in cigarette smoke, gasoline, and motor vehicle exhaust. Unfortunately the widespread use is also associated with a significant risk of malignancies. Leukemias, lymphomas, and lung cancers are among the malignancies commonly linked to benzene exposure. Studies have described various pathophysiological mechanisms involving interactions between the immune system, stem cells, and oxidative stress. These changes are linked to chromosomal abnormalities and the development of a mutator phenotype. In addition to cancers, benzene is associated with the acceleration of lifestyle diseases such as cardiovascular disease and metabolic syndrome. Other carcinogens include ultraviolet radiation, processed meat, and various air pollutants. Authorities have implemented various regulations have been established to limit exposure to such hazardous chemicals. Additionally, recommendations have been issued regarding actions to take in the event of acute benzene exposure. By raising awareness and enforcing stringent laws, the incidence of benzene-associated cancers can decline.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.