Evidence map›Paper›PMID 41180633›Full record

ArticleAnnals of medicine and surgery (2012)2025

AI in drug repurposing for cancer therapies.

Muhammad Nabeel Saddique, Ursula Abu Nahla

Abstract readLetter
In one paragraph

Article in Annals of medicine and surgery (2012), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Muhammad Nabeel SaddiqueKing Edward Medical University, Lahore, Pakistan.
Ursula Abu NahlaFaculty of Medicine, Hebron University, Hebron, Palestinian Territory, Occupied.ORCID https://orcid.org/0009-0001-2356-0751

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Artificial intelligence (AI) is transforming drug discovery by enabling the rapid identification of existing drugs with potential anti-cancer properties, a process known as drug repurposing. This approach offers a cost-effective and time-efficient alternative to traditional drug development, particularly in oncology, where the need for novel therapies is urgent. AI-driven methods, including machine learning (ML) and deep learning (DL), analyze vast datasets to uncover hidden drug-disease relationships, predict drug efficacy, and optimize therapeutic combinations. This letter highlights the transformative potential of AI in drug repurposing for cancer therapies, supported by successful examples from recent research. We also discuss the challenges and ethical considerations of integrating AI into drug repurposing efforts, emphasizing the need for robust validation and regulatory oversight to ensure patient safety and efficacy.

Indexed as

artificial intelligencecancer researchclinical trialsdata analysisdrug repurposingpatient recruitment

Identifiers

PMID41180633
PMCPMC12577870

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.