Evidence map›Paper›PMID 41180619›Full record

ReviewAnnals of medicine and surgery (2012)2025

Alpha-1 antitrypsin deficiency: genetics, clinical manifestations, AI prognostics, and advanced imaging in liver disease.

Islam Rajab, Monica Pernia Marin, Abdalhakim Shubietah, Ayman Khaled, Mohammad Bdair, Maram M Abukhalil, Hammam Jallad, Abdallah Hussein, Samia Ammar Aldwaik, Mary M Salvatore

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Annals of medicine and surgery (2012), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Islam RajabDepartment of Thoracic Radiology, Columbia University Irving Medical Center, New York, NY, USA.
Monica Pernia MarinDepartment of Neurology, Division of Neurology-oncology at Columbia University Irving Medical Center, New York, NY, USA.
Abdalhakim ShubietahInternal Medicine Department, Advocate Illinois Masonic Medical Center, Chicago, IL, USA.
Ayman KhaledDepartment Of Medicine, Faculty of Medicine and Health Sciences, An-Najah National University, Nablus, Palestine.
Mohammad BdairDepartment Of Medicine, Faculty of Medicine and Health Sciences, An-Najah National University, Nablus, Palestine.
Maram M AbukhalilDepartment Of Medicine, Faculty of Medicine and Health Sciences, An-Najah National University, Nablus, Palestine.
Hammam JalladDepartment Of Medicine, Faculty of Medicine and Health Sciences, An-Najah National University, Nablus, Palestine.ORCID https://orcid.org/0009-0009-5023-1361
Abdallah HusseinInternal Medicine Department, Virtua Health Inc, Voorhees, NJ, USA.
Samia Ammar AldwaikDepartment Of Medicine, Faculty of Medicine and Health Sciences, An-Najah National University, Nablus, Palestine.
Mary M SalvatoreDepartment of Radiology, Columbia University Irving Medical Center, New York, NY, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alpha-1 antitrypsin deficiency (AATD) is a genetic disorder caused by mutations in the

Indexed as

alpha-1 antitrypsin deficiencyartificial intelligenceCOPDemerging therapiesimaging technologiesliver diseaseSERPINA1siRNA therapy

Identifiers

PMID41180619
PMCPMC12578108

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.