ReviewAnnals of medicine and surgery (2012)2025
Hyperkalemia-related mortality trends in cardiac arrest: a 1999-2020 analysis in the United States.
Review in Annals of medicine and surgery (2012), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed.
- Clinical impact of an EHR-integrated hyperkalemia management system: a real-world study of 10,934 episodes.Renal failure · 2026Article
- Sex differences in potassium regulation: evidence, molecular mechanisms and clinical implications.Biology of sex differences · 2026Review
- Treatment of Hyperkalemia-Induced-Cardiac-Arrest by Dynamic Electrocardiogram and Point-of-Care-testing Potassium: A Case Report.Clinical medicine insights. Case reports · 2026Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: In the United States (US), cardiac arrest is still the important cause of fatality, yet there is limited exploration of mortality linked to hyperkalemia. This study aimed to analyze the trends and regional variations in the mortality of cardiac arrest due to hyperkalemia in people aged 15 years and older. Methods: The study examined mortality from cardiac arrest related to hyperkalemia in people aged 15 years and older via the CDC WONDER database, which spans from 1999 to 2020. Age-adjusted mortality rates (AAMRs) and the annual percent change (APC) per 100 000 individuals were calculated, with strata based on year, sex, age groups, urbanization, race and geographic region. Results: Between 1999 and 2020, 36 840 cardiac arrest deaths related to hyperkalemia were reported among those aged 15 years and above. The overall AAMR declined from 5.9 in 1999 to 4.9 in 2007, followed by increases to 7.7 and 9.5 in 2018 and 2020, respectively. Males consistently presented higher AAMRs than females, and the highest AAMR was found in NH Black or African American patients. Crude mortality rate (CMR) was higher among people of age 85 years and above. Conclusion: Since 2007, mortality due to cardiac arrest related to hyperkalemia in individuals aged 15 years and above has increased. Interventions to manage hyperkalemia are essential to limit rising mortality rates, especially among specific demographic groups and geographic regions.
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