Evidence map›Paper›PMID 41180610›Full record

ArticleInfection and drug resistance2025

Integrated Molecular Diagnostics Unmask

Qianyun Deng, Yujing Yang, Siyi Gao, Mengdi Lu, Yunhu Zhao, Zixia Wang

Abstract readCase Reports
In one paragraph

Article in Infection and drug resistance, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Qianyun Deng *Department of Laboratory Medicine, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, Guangdong, 510000, People's Republic of China.ORCID 0000-0003-1059-1919
Yujing Yang *Department of Laboratory Medicine, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, Guangdong, 510000, People's Republic of China.
Siyi GaoInspection Section, Luonan County Chinese Medicine Hospital, Luonan, Shangluo, Shaanxi, 726100, People's Republic of China.
Mengdi LuDepartment of Laboratory Medicine, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, Guangdong, 510000, People's Republic of China.
Yunhu ZhaoDepartment of Laboratory Medicine, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, Guangdong, 510000, People's Republic of China.ORCID 0000-0002-3745-014X
Zixia WangDepartment of Laboratory Medicine, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, Guangdong, 510000, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Case Description: A 57-year-old woman with rheumatic heart disease, chronic renal failure, and immunosuppression presented with acute respiratory failure. Initial investigations revealed leukocytosis (19.03×10 Conclusion: Integrated molecular diagnostics enable rapid pathogen identification in critically ill immunocompromised hosts. Multi-platform verification (isothermal amplification/dPCR/mNGS) overcomes technical limitations of single methods, while serial biomarker monitoring optimizes antimicrobial stewardship for mixed infections.

Indexed as

digital PCRimmunocompromised hostLegionella pneumophilametagenomic next-generation sequencingmixed infection

Identifiers

PMID41180610
PMCPMC12577587

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.