ArticleJournal of diabetes research2025
Association of Geriatric Nutritional Risk Index With Cardiovascular and All-Cause Mortality Among US Elderly Adults With Diabetic Nephropathy.
Article in Journal of diabetes research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Association between insulin resistance surrogate markers and cardiovascular disease risk in individuals with subclinical metabolic disorders: a prospective cohort study based on baseline levels, cumulative exposure, and longitudinal trajectories.Cardiovascular diabetology · 2026Article
- Associations of Diabetes Mellitus Status and Geriatric Nutritional Risk Index with the Gut Microbiota in Nursing-Home Residents.Nutrients · 2026Article
- The Impact of Body Mass Index and Nutritional Status on Cardiac Electrophysiological Balance Using ICEB and ICEBc: A Cross-Sectional Approach.Journal of cardiovascular development and disease · 2026Article
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3 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Objectives: This study examines the association between the Geriatric Nutritional Risk Index (GNRI) and all-cause and cardiovascular disease (CVD) mortality in elderly diabetic nephropathy (DN) patients in the United States. Methods: Participants were categorized into three GNRI-based groups: (1) moderate to severe malnutrition (M/S) risk (< 92), (2) low risk (92-98), and (3) no risk (> 98). The primary outcomes were all-cause and CVD mortality. Cox proportional hazards regression and competing risk analysis were used to estimate hazard ratios (HRs) and 95% confidence intervals (CIs). Results: Among 1790 DN patients (mean age 71.24 ± 7.17 years; weighted 55.0% male, 45.0% female), over 11,724 person-years (mean follow-up 6.56 ± 4.59 years), 274 (15.3%) died from CVD and 914 (51.1%) from all causes. The M/S risk group had a 143% increased all-cause mortality risk (HR 2.43; 95% CI, 1.25-5.80), while the low risk group had a 56% increased risk (HR 1.56; 95% CI, 1.19-2.38), compared to the no risk group. No significant correlation was observed between GNRI and CVD mortality. In gender-specific analysis, the M/S risk group had a higher all-cause mortality risk in males (HR 2.50; 95% CI, 1.04-5.99) than in females (HR 1.62; 95% CI, 0.83-3.15). Conclusions and Implications: A lower GNRI is associated with higher all-cause mortality in elderly DN patients, particularly in males, but not with CVD mortality. GNRI may be a useful prognostic tool for mortality risk assessment in this population.
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