Evidence map›Paper›PMID 41180525›Full record

ArticleFrontiers in neurology2025

Clinical efficacy observation and safety evaluation of acupuncture for intractable facial paralysis: a single-blinded randomized controlled pilot trial.

Hongyu Xie, Yu Xia, Lele Zhang, Aihong Yuan, Jun Yang, Ling Cheng, Ting Gao, Bo Li, Xuwen Yuan, Min Ye and 6 more

Abstract read
In one paragraph

Article in Frontiers in neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Hongyu Xie *Second Department of Acupuncture Rehabilitation, The First Affiliated Hospital of Anhui University of Chinese Medicine, Hefei, China.
Yu Xia *Anhui University of Chinese Medicine, Hefei, China.
Lele Zhang *Anhui University of Chinese Medicine, Hefei, China.
Aihong YuanSecond Department of Acupuncture Rehabilitation, The First Affiliated Hospital of Anhui University of Chinese Medicine, Hefei, China.
Jun YangSecond Department of Acupuncture Rehabilitation, The First Affiliated Hospital of Anhui University of Chinese Medicine, Hefei, China.
Ling ChengAnhui University of Chinese Medicine, Hefei, China.
Ting GaoFourth Department of Geriatric Diseases, The Second Affiliated Hospital of Anhui University of Chinese Medicine, Hefei, China.
Bo LiSecond Department of Acupuncture Rehabilitation, Shuguang Hospital Anhui Branch Affiliated to Shanghai University of Traditional Chinese Medicine, Hefei, China.
Xuwen YuanDepartment of Acupuncture, Bozhou Hospital of Traditional Chinese Medicine, Bozhou, China.
Min YeAnhui University of Chinese Medicine, Hefei, China.
Wenjing KanAnhui University of Chinese Medicine, Hefei, China.
Jie ShiSecond Department of Acupuncture Rehabilitation, The First Affiliated Hospital of Anhui University of Chinese Medicine, Hefei, China.
Zhen LiuSecond Department of Acupuncture Rehabilitation, The First Affiliated Hospital of Anhui University of Chinese Medicine, Hefei, China.
Fei YuanSecond Department of Acupuncture Rehabilitation, The First Affiliated Hospital of Anhui University of Chinese Medicine, Hefei, China.
Chao ZhouDepartment of Traditional Chinese Medicine, First Affiliated Hospital of Anhui Medical University, Hefei, China.
Xiaojun LiuBozhou Vocational and Technical College, Bozhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Acupuncture can effectively improve the clinical symptoms of intractable facial paralysis (IFP). However, it is not yet clear whether the use of acupuncture manipulation affects the therapeutic effect. This study aims to conduct a preliminary exploration of the clinical efficacy and safety of acupuncture treatment for IFP using acupuncture manipulation. Methods: A single-center, single-blind, randomized controlled pilot trial was conducted from December 2022 to December 2023, involving 40 IFP participants, divided into the ordinary acupuncture group (OAG, Results: After the second treatment course, the difference in the Anzhong Facial Paralysis Precision Scale (Oral Commissure Ptosis Grading Scale) levels between the two groups began to show statistical significance ( Conclusion: Acupuncture has a good therapeutic effect on IFP, and the combination of characteristic acupuncture manipulation has a better therapeutic effect. However, these conclusions require further validation in larger clinical studies. Clinical trial registration: https://www.chictr.org.cn/, Identifier ChiCTR2200065442.

Indexed as

acupunctureAnzhong Facial Paralysis Precision Scale (Oral Commissure Ptosis Grading Scale)intractable facial paralysisrandomized controlled pilot trialsurface electromyography

Identifiers

PMID41180525
PMCPMC12571635

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.