Evidence map›Paper›PMID 41180516›Full record

ArticlePRX life

Protein folding as a jamming transition.

Alex T Grigas, Zhuoyi Liu, Jack A Logan, Mark D Shattuck, Corey S O'Hern

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in PRX life. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Residue burial encodes a protein's fold.bioRxiv : the preprint server for biology · 2026
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Alex T GrigasGraduate Program in Computational Biology and Bioinformatics, Yale University, New Haven, Connecticut, 06520, USA.
Zhuoyi LiuDepartment of Mechanical Engineering and Materials Science, Yale University, New Haven, Connecticut, 06520, USA.
Jack A LoganDepartment of Mechanical Engineering and Materials Science, Yale University, New Haven, Connecticut, 06520, USA.
Mark D ShattuckBenjamin Levich Institute and Physics Department, The City College of New York, New York, New York 10031, USA.
Corey S O'HernDepartment of Mechanical Engineering and Materials Science, Yale University, New Haven, Connecticut, 06520, USA.

Funding

MEDICAL INFORMATICS RESEARCH TRAINING AT YALET15LM007056 · NLM · YALE UNIVERSITY · PI Mark Bender Gerstein, LUCILA OHNO-MACHADO · 1987 to 2026
$22.2M
Convergent graduate training in systems biology at YaleT32GM145452 · NIGMS · YALE UNIVERSITY · PI KATHRYN MILLER-JENSEN, Corey O'Hern · 2022 to 2026
$1.0M
NIGMS NIH HHS T32 GM145452NLM NIH HHS T15 LM007056
6 · The paper itself

Abstract

Proteins fold to a specific functional conformation with a densely packed core that controls their stability. Despite their importance, we lack a quantitative explanation for why all protein cores, regardless of their overall fold, possess the same average packing fraction

Identifiers

PMID41180516
PMCPMC12573692

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.