Evidence map›Paper›PMID 41180504›Full record

ReviewTzu chi medical journal

Tumor organoids: A review of culture methods, applications in cancer research, precision medicine, and drug development.

Chuan-Hsin Chang, Chung-Che Tsai, Ching-Feng Cheng, Tin-Yi Chu, Chun-Pin Chiang, Yi-Pang Lee, Chao-Chuan Wu, Jiann-Hwa Chen, Chan-Yen Kuo, Po-Chih Hsu

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Tzu chi medical journal. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Organoid technology in cancer research.Molecular biomedicine · 2026
    Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Chuan-Hsin Chang *Department of Research, Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, New Taipei, Taiwan.
Chung-Che Tsai *Department of Research, Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, New Taipei, Taiwan.
Ching-Feng ChengDepartment of Pediatrics, Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, New Taipei, Taiwan.
Tin-Yi ChuDepartment of Research, Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, New Taipei, Taiwan.
Chun-Pin ChiangInstitute of Oral Medicine and Materials, College of Medicine, Tzu Chi University, Hualien, Taiwan.
Yi-Pang LeeInstitute of Oral Medicine and Materials, College of Medicine, Tzu Chi University, Hualien, Taiwan.
Chao-Chuan WuSchool of Medicine, Tzu Chi University, Hualien, Taiwan.
Jiann-Hwa ChenSchool of Medicine, Tzu Chi University, Hualien, Taiwan.
Chan-Yen KuoDepartment of Research, Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, New Taipei, Taiwan.
Po-Chih HsuSchool of Medicine, Tzu Chi University, Hualien, Taiwan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Three-dimensional (3D) culture systems known as organoids have emerged as powerful preclinical models for human tumors, supporting the advancement of cancer research from the laboratory to clinical application. They have transformed preclinical cancer research by preserving the complexity and biological characteristics of human cancers. Organoids more accurately replicate the intricate architecture and microenvironment of clinical tumors compared to conventional

Indexed as

Cancer researchOrganoidsPatient-derived tumor organoidsThree-dimensional culture systemsTumor environment

Identifiers

PMID41180504
PMCPMC12574996

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.