Evidence map›Paper›PMID 41180469›Full record

ArticleRSC medicinal chemistry2025

Designing halogen-free metal-phenolic imidazolium poly(ionic liquids) with multi-functional antibacterial, anti-inflammatory and cell proliferation properties for infected wounds.

Danni Wang, Xiaodong He, Yingcui Cai, Chengju Sheng, Yuexiao Jia, Xiaojia Huang, Jia Ling Celestine Loh, Ruzhi Zhang, Mingmei Yang, Liqun Xu and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in RSC medicinal chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Danni WangSchool of Medical and Health Engineering, Changzhou University Changzhou Jiangsu 213164 China zhouchao@cczu.edu.cn.
Xiaodong HeBRICS Joint Laboratory on Biomedical Materials, School of Materials and Energy, Southwest University Chongqing 400715 China xulq@swu.edu.cn.ORCID https://orcid.org/0000-0002-4305-8304
Yingcui CaiSchool of Medical and Health Engineering, Changzhou University Changzhou Jiangsu 213164 China zhouchao@cczu.edu.cn.
Chengju ShengSchool of Chemistry and Chemical Engineering, Southwest University Chongqing 400715 China.
Yuexiao JiaSchool of Medical and Health Engineering, Changzhou University Changzhou Jiangsu 213164 China zhouchao@cczu.edu.cn.
Xiaojia HuangSchool of Medical and Health Engineering, Changzhou University Changzhou Jiangsu 213164 China zhouchao@cczu.edu.cn.
Jia Ling Celestine LohDUKE-NUS Medical School, National University of Singapore 169857 Singapore.
Ruzhi ZhangDepartment of Dermatology, The Second Affiliated Hospital of Wannan Medical college 10 Kangfu Road Wuhu Anhui 241000 China zhangruzhi628@163.com.
Mingmei YangDepartment of Dermatology, Affiliated Changzhou Children's Hospital of Nantong University Changzhou Jiangasu 213000 China.
Liqun XuBRICS Joint Laboratory on Biomedical Materials, School of Materials and Energy, Southwest University Chongqing 400715 China xulq@swu.edu.cn.ORCID https://orcid.org/0000-0002-6780-114X
Chao ZhouSchool of Medical and Health Engineering, Changzhou University Changzhou Jiangsu 213164 China zhouchao@cczu.edu.cn.ORCID https://orcid.org/0000-0002-8952-8690

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Infected wounds are challenging to heal because they are complicated by bacterial infections, persistent inflammation, and impaired cell proliferation. Recently, imidazolium poly(ionic liquids) (PILs), as highly effective antibacterial agents, have been developed for infected wound healing. However, traditional imidazolium-based PILs containing halogen groups have shown potential cytotoxicity. In this study, we designed halogen-free metal-phenolic imidazolium PILs (HMPIPs) with antibacterial, anti-inflammatory and cell proliferation properties. Firstly, poly(vinyl-butylimidazolium dihydroxyphenylpropionic acid) (PVD) was synthesized

Identifiers

PMID41180469
PMCPMC12577589

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.