Evidence map›Paper›PMID 41180391›Full record

ArticleAging medicine (Milton (N.S.W))2025

Dose-Response Associations of Grip Strength and Gait Speed With Multidimensional Mental Health.

Jiapei Wei, Liming Zhang, Shengyi Li, Xucheng Wu, Xingqi Cao, Liying Chen, Zuyun Liu, Yangzhen Lu, Xuan Ge

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In one paragraph

Article in Aging medicine (Milton (N.S.W)), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jiapei WeiDepartment of General Practice Dongyang People's Hospital Jinhua Hangzhou China.
Liming ZhangSecond Affiliated Hospital, School of Public Health, Zhejiang Key Laboratory of Intelligent Preventive Medicine, Zhejiang University School of Medicine Hangzhou Zhejiang China.ORCID https://orcid.org/0000-0001-9049-9930
Shengyi LiDepartment of Biostatistics, Johns Hopkins Bloomberg School of Public Health Baltimore Maryland USA.
Xucheng WuSecond Affiliated Hospital, School of Public Health, Zhejiang Key Laboratory of Intelligent Preventive Medicine, Zhejiang University School of Medicine Hangzhou Zhejiang China.
Xingqi CaoDepartment of General Practice Sir Run Run Shaw Hospital, Zhejiang University School of Medicine Hangzhou Zhejiang China.
Liying ChenDepartment of General Practice Sir Run Run Shaw Hospital, Zhejiang University School of Medicine Hangzhou Zhejiang China.
Zuyun LiuSecond Affiliated Hospital, School of Public Health, Zhejiang Key Laboratory of Intelligent Preventive Medicine, Zhejiang University School of Medicine Hangzhou Zhejiang China.
Yangzhen LuDepartment of General Practice Dongyang People's Hospital Jinhua Hangzhou China.
Xuan GeHealth Management Center, Dongyang People's Hospital Jinhua Zhejiang China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: We aimed to examine the dose-response associations of grip strength and gait speed with multidimensional mental health among Chinese adults. Methods: Cross-sectional data on 661 adults from the ZheJiang longitudinal Study of Healthy Aging (JASHA) were utilized. Grip strength and gait speed were measured during physical examinations. Multidimensional mental health, covering cognitive function (the Auditory Verbal Learning Test (AVLT), the Montreal Cognitive Assessment (MoCA) test, and the Digit Symbol Substitution Test (DSST)), depressive symptoms (the Center for Epidemiologic Studies Depression (CES-D) Scale), and psychological distress (the Perceived Stress Scale (PSS)), were assessed via standard questionnaires. Multivariable linear regression models and restricted cubic splines were applied to examine these associations. Results: We found linear dose-response associations of grip strength and gait speed with most dimensions of mental health. For instance, higher grip strength was positively associated with higher cognitive function scores (AVLT_N3: Conclusions: In this sample spanning a wide range of ages, we found linear significant associations of grip strength and gait speed with most dimensions of mental health. The finding unveils the intrinsic connections between musculoskeletal function and mental health, highlighting the potential of preserving musculoskeletal function, such as via maintaining regular physical exercise, to prevent mental health disorders, especially for females and older adults.

Indexed as

Dose–response associationGait speedGrip strengthMental health

Identifiers

PMID41180391
PMCPMC12576581

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.