ArticleBMJ public health2025
Community-based serological screening for Chagas disease in London: a cross-sectional, observational pilot study.
Article in BMJ public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
4 citing papers in PubMed.
- Making the invisible visible: maternal and child health inequalities for Latin Americans in the UK.The Lancet regional health. Europe · 2026Article
- Cardiac imaging in Chagas cardiomyopathy for phenotypic characterisation and risk stratification.Heart failure reviews · 2026Review
- Catch-Up Screening to Improve Detection of Congenital Chagas Disease in a Nonendemic Setting.The American journal of tropical medicine and hygiene · 2026Article
- Primary care and community-based screening for Chagas disease in London, United Kingdom, August 2023 to January 2025.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2026Observational
Corrections and comments
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Authors and funding
39 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Chagas disease (CD) is increasingly recognised as a public health problem in non-endemic settings. The UK is home to a large Latin American migrant population; yet, there is no formal screening programme for CD.The aim of this study was to co-design and evaluate a community-based screening initiative for CD in Latin American migrants in London, UK. Methods: This was a cross-sectional, observational pilot study, using questionnaires and point of care tests (POCTs: finger-prick lateral flow assays for qualitative detection of Immunoglobulin G (IgG) to Results: 334 adult participants (254 at CD-specific events and 80 at other events) participated in screening between December 2021 and May 2023. All were first-generation or second-generation migrants from South America, Central America or Mexico. 206 (62%) were born in Bolivia and 223 (67%) were women.A total of 79 out of 334 (24%) participants screened positively, of whom 77 (97%) attended for confirmatory laboratory serology and 70 (21% total population screened) were confirmed as true cases (two laboratory-performed serological assays positive). The POCT-PPV overall was 91%. 90% of the true confirmed cases detected through community screening were still engaged in specialist care at a mean of 2.5 years follow-up. The number needed to screen to link one confirmed case into specialist care was 5.3. Conclusions: Active case finding through delivery of targeted community-based screening using POCTs at either dedicated events or as pop-up testing at other events can effectively identify people with CD, with a high yield and minimal loss to follow-up.
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