Evidence map›Paper›PMID 41180348›Full record

ArticleCJC open2025

Factors Influencing Internal Medicine Resident Beta-Blocker Discontinuation in Acute Decompensated Heart Failure.

Daniel Boctor, Samuel B Brusca, Gurpreet Dhaliwal, Matthew D Ponzini, Noelle Boctor, Connor G O'Brien

Abstract read
In one paragraph

Article in CJC open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Daniel BoctorDepartment of Medicine, University of California, San Francisco, San Francisco, California, United States.
Samuel B BruscaDepartment of Medicine, University of California, San Francisco, San Francisco, California, United States.
Gurpreet DhaliwalDepartment of Medicine, University of California, San Francisco, San Francisco, California, United States.
Matthew D PonziniClinical and Translational Science Center, University of California, Davis, Sacramento, California, United States.
Noelle BoctorDepartment of Internal Medicine, University of California, Davis, Sacramento, California, United States.
Connor G O'BrienDepartment of Medicine, University of California, San Francisco, San Francisco, California, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Heart failure is one of the leading causes of hospital admissions in North America. Although guidelines support the continuation of beta blockers on admission, hemodynamic considerations and mechanistic reasoning may prompt beta blocker discontinuation even in the absence of contraindications. Resident physicians often face this dilemma and are an important group in which to evaluate this decision-making. Methods: Internal medicine residents at two institutions were presented with two scenarios: 1) whether to continue outpatient metoprolol succinate for a patient without evidence of shock admitted with acute decompensated heart failure (ADHF) and 2) beta blocker selection during a patient's index presentation with heart failure. Results: 142 of 287 (49.5%) residents responded to the survey. In scenario 1, 61% of residents discontinued metoprolol succinate on admission. The top three concerns about continuing metoprolol were precipitating cardiogenic shock, discomfort with the vital signs range, and attending physician disagreement. In scenario 2, 74% of participants initiated metoprolol succinate, 25% chose carvedilol, and only 1 participant chose bisoprolol. Conclusions: Drivers of inpatient beta blocker discontinuation should be considered by internal medicine training programs and heart failure guideline writers when opportunities arise to enact practice changes that align with evidence.

Indexed as

acute decompensated heart failurebeta-blocker withdrawalheart failuremechanistic reasoningmedical decision-makingresident physicians

Identifiers

PMID41180348
PMCPMC12572888

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.