Evidence map›Paper›PMID 41180293›Full record

ArticleAntimicrobial stewardship & healthcare epidemiology : ASHE2025

Implementation of a hospital-wide EHR-integrated antibiotic challenge order set.

Wesley Hoffmann, Shivani Patel, Shemual Tsai, Natalie Finch, Muhammad Yasser Alsafadi

Abstract read
In one paragraph

Article in Antimicrobial stewardship & healthcare epidemiology : ASHE, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Wesley HoffmannDepartment of Pharmacy, Houston Methodist Hospital, Houston, TX, USA.ORCID https://orcid.org/0000-0002-1180-021X
Shivani PatelDepartment of Pharmacy, Houston Methodist Hospital, Houston, TX, USA.ORCID https://orcid.org/0009-0001-6909-4071
Shemual TsaiDepartment of Pharmacy, Houston Methodist Hospital, Houston, TX, USA.ORCID https://orcid.org/0009-0002-6222-0829
Natalie FinchDepartment of Pharmacy, Houston Methodist Hospital, Houston, TX, USA.ORCID https://orcid.org/0009-0009-0888-5943
Muhammad Yasser AlsafadiDivision of Infectious Diseases, Houston Methodist Hospital, Houston, TX, USA.ORCID https://orcid.org/0000-0003-0276-7910

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We implemented an electronic health record-integrated order set to standardize direct antibiotic challenges for patients with reported antibiotic allergies across nine healthcare facilities. In the first year, 104 patients were challenged (79% oral; 39% two-step). Embedded antibiotic selection, dosage, monitoring parameters, reaction guidance, and rescue medications facilitated uptake by hospitalists and subspecialists.

Identifiers

PMID41180293
PMCPMC12571674

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.