Evidence map›Paper›PMID 41180291›Full record

ArticleAntimicrobial stewardship & healthcare epidemiology : ASHE2025

Beyond the bugs: why toxin detection is key in two-tiered

David Goldmeier, Michael Parry, Marina Mirkovic, Asha Shah, Shweta Karki, Forugh Homayoonrooz, Suzanne J Rose

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Antimicrobial stewardship & healthcare epidemiology : ASHE, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

David GoldmeierGeorge Washington University Hospital, Washington, DC, USA.
Michael ParryStamford Hospital, Department of Medicine, Stamford, CT, USA.ORCID https://orcid.org/0000-0003-0341-3989
Marina MirkovicStamford Health Medical Group, Stamford, CT, USA.
Asha ShahStamford Hospital, Department of Medicine, Stamford, CT, USA.
Shweta KarkiStamford Health Department of Research and Discovery, Stamford, CT, USA.ORCID https://orcid.org/0009-0000-7630-6645
Forugh HomayoonroozStamford Hospital, Department of Medicine, Stamford, CT, USA.
Suzanne J RoseStamford Health Department of Research and Discovery, Stamford, CT, USA.ORCID https://orcid.org/0000-0001-5770-826X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: We recently added Design: Retrospective chart review. Setting: 305-bed acute care urban teaching hospital. Patients: All inpatients admitted who tested positive for Methods: On April 1, 2023, the two-tier testing algorithm was implemented for patients who tested positive by PCR. The EMR was reviewed through May 1, 2024, to determine whether toxin-positive patients differed from toxin-negative patients with respect to their demographics, clinical characteristics, outcomes, and initiation of antibiotic treatment. Results: Of 147 consecutive Conclusion: Our study supports previous findings that a two-tier testing strategy effectively identifies active

Identifiers

PMID41180291
PMCPMC12571672

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.