ReviewFrontiers in veterinary science2025
Heat stress affects dairy cow performance via oxidative stress, hypothalamic-pituitary-adrenal axis, gut microbiota, and multi-dimensional mitigation.
Review in Frontiers in veterinary science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed.
- Impact of Climate Change on Farm Animals: Physiological Mechanisms, Health and Productivity, and Integrated Adaptation Strategies.Veterinary sciences · 2026Review
- Oxidative Stress in Animals: A Systematic Analysis from Signaling Pathways to Biological Effects.Life (Basel, Switzerland) · 2026Review
- Oral Supplementation with a Kudzu Root-Black Soybean Blend Attenuates Ovarian Dysfunction in Mice: Implications for Its Potential Use as a Dietary Supplement in Animal Nutrition.Animals : an open access journal from MDPI · 2026Article
- A Blend of Essential Oils Plus Vitamin D3 Combined withAnimals : an open access journal from MDPI · 2026Article
- Nuclear Stress Bodies and Mitochondrial Signal Transduction Regulate Thermotolerance in Cattle: Insights Into Molecular Mechanisms.Animal genetics · 2026Review
- Nutritional Strategies to Mitigate Heat Stress in Cattle: A Narrative Review.Microorganisms · 2026Review
- Rumen-host crosstalk: an amplifier of systemic pathology in heat-stressed ruminants.Frontiers in microbiology · 2026Review
- Research progress on the mechanisms and intervention strategies of microbiota-gut-brain axis dysfunction under heat stress.Frontiers in physiology · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Against the backdrop of global warming, heat stress has become one of the greatest challenges facing the dairy industry. This review systematically summarizes the multi-dimensional impacts of heat stress on dairy cows and corresponding mitigation strategies under global warming. It covers the evaluation indicators (temperature-humidity index, physiological and behavioral indicators) and classification of heat stress. It analyzes the negative effects on dairy cows' reproductive performance (e.g., oocyte and sperm damage, hormonal disorders, impaired fetal development) and production performance (e.g., reduced milk yield, deteriorated milk composition). These effects are mediated by physiological mechanisms such as oxidative stress imbalance, hypothalamic-pituitary-adrenal axis (HPA axis) activation, cellular structural damage, altered gene expression, and disrupted host-gut microbiota interactions. Additionally, the review integrates interdisciplinary mitigation strategies including environmental optimization, nutritional regulation, genetic breeding, and intelligent monitoring. It provides theoretical and practical references for constructing a sustainable heat stress prevention and control system.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.