ArticleFrontiers in veterinary science2025
Evaluation of the cardiorespiratory and antinociceptive effects of the total intravenous anesthesia technique with xylazine-butorphanol-propofol compared to isoflurane in calves under experimental laparotomy.
Article in Frontiers in veterinary science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Comparison of Seda-Block and Xylazine-Ketamine Anaesthesia for Metacarpal and Radioulnar Osteosynthesis in Calves.Veterinary medicine and science · 2026Article
- Effects of the continuous rate infusion of propofol with or without fentanyl on ruminal motility in calves.Brazilian journal of veterinary medicine · 2026Article
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Authors and funding
5 authors.
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Abstract
A novel total intravenous anesthesia (TIVA) technique combining xylazine (0.1 mg/mL), butorphanol (0.01 mg/mL), and propofol (2 mg/mL) in a 5% dextrose solution (XBP) has shown promising results in calves. In the present study, we compared XBP-TIVA with isoflurane (ISO) inhalation anesthesia during experimental laparotomy in calves, evaluating cardiorespiratory and antinociceptive effects. Fourteen clinically healthy male and female calves (body weight: 28.5-155.0 kg; age: 17-186 days) were randomly assigned to receive XBP-TIVA (continuous infusion at a rate of 6 mL/kg/h) or ISO inhalation anesthesia (end-tidal concentration: 1.3 ± 0.1%) for 60 min during laparotomy. We measured rectal temperature (RT), heart rate (HR), arterial blood pressure, and arterial blood gas values. Then, HR variability (HRV) components and stress hormones were measured to analyze autonomic nervous system and neuroendocrine responses to nociceptive stimuli. Measurements were taken before drug administration (baseline) and at 5-min or 15-min intervals after anesthesia maintenance. Nociceptive stimuli were administered, including skin and muscle incision, intestinal manipulation, muscle suture, and skin suture. The statistical significance level was set at
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