ReviewWorld journal of stem cells2025
Silent saboteurs: How microplastics disrupt stem cells and tissue regeneration.
Review in World journal of stem cells, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Microplastics (MPs), defined as plastic particles with diameters less than 5 mm, have become significant global environmental contaminants. MPs accumulate in human tissues and organs, raising significant concerns about their potential biological toxicity. Evidence indicates that MPs and associated toxins disrupt stem cell self-renewal, proliferation, and differentiation processes essential for tissue regeneration and systemic homeostasis, yet research on MP-induced stem cell damage remains limited. To identify relevant and recent studies, we searched the PubMed database using title and abstract fields. This review synthesizes current evidence across organ systems, including nervous, hematopoietic, skeletal, and urinary systems, to systematically categorize phenotypic disruptions and underlying mechanisms in stem cells. We further evaluate the utility of stem-cell-derived organoids in modeling organ-specific MP toxicity. By consolidating fragmented findings, this work provides a critical framework for assessing MP risks to tissue regeneration and informs strategies for regenerative medicine and public health protection.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.