ArticleSAGE open medicine2025
Role of platelet-related parameters in prediction of development and severity of preeclampsia (PE): an observational prospective cohort study.
Article in SAGE open medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Role of second-trimester hematological and biochemical indicators in predicting preeclampsia: a retrospective study.BMC pregnancy and childbirth · 2026Article
- First-trimester β-hCG, PAPP-A, and NLR in relation to preeclampsia and perinatal outcomes: A case-control study.Science progressArticle
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objectives: Preeclampsia (PE) is a major contributor to maternal and foetal morbidity and mortality. Early identification of women at risk is crucial for timely intervention, yet a cost-effective and reliable screening tool remains unavailable. This study aimed to evaluate the role of platelet-related parameters-platelet count (PC), mean platelet volume (MPV), plateletcrit (PCT), platelet distribution width (PDW), neutrophil-to-lymphocyte ratio (NLR), and platelet-to-lymphocyte ratio (PLR)-in predicting the development and severity of PE. Methods: This prospective observational cohort study was conducted at AIIMS Patna between January and November 2021. Pregnant women enrolled before 14 weeks of gestation were followed throughout pregnancy. Platelet parameters were measured at three gestational intervals: 10 to 14 weeks, 24 to 28 weeks, and 32 to 36 weeks. Data were analysed using SPSS v22, employing chi-square tests, Results: Among 728 participants, 9.3% developed PE. Risk was significantly higher in primigravida women ( Conclusion: Platelet indices, particularly PCT and NLR, demonstrated a significant association with PE in early pregnancy, while MPV was significantly elevated in late pregnancy. These findings suggest potential utility in risk stratification, though further studies are required to validate their predictive value before routine use in early screening.
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