Evidence map›Paper›PMID 41180113›Full record

ArticleClinical, cosmetic and investigational dermatology2025

Successful Treatment with Secukinumab in an Erythrodermic Psoriasis Patient with End-Stage Kidney Disease on Hemodialysis: A Case Report.

Shixuan Zhang, Panpan Liu, Sitong Liu, Minghuan He, Song Zheng, Xiaodong Sun, Ruiqun Qi, Xinghua Gao, Lili Zhu

Abstract readCase Reports
In one paragraph

Article in Clinical, cosmetic and investigational dermatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Shixuan ZhangDepartment of Dermatology, the People's Hospital of Liaoning Province, Shenyang, Liaoning Province, 110016, People's Republic of China.
Panpan LiuDepartment of Nephrology, the People's Hospital of Liaoning Province, Shenyang, Liaoning Province, 110016, People's Republic of China.
Sitong LiuDepartment of Dermatology, the People's Hospital of Liaoning Province, Shenyang, Liaoning Province, 110016, People's Republic of China.
Minghuan HeDepartment of Dermatology, the People's Hospital of Liaoning Province, Shenyang, Liaoning Province, 110016, People's Republic of China.
Song ZhengDepartment of Dermatology, the First Hospital of China Medical University, Shenyang, Liaoning Province, 110000, People's Republic of China.
Xiaodong SunDepartment of Dermatology, Shenyang No. 7 People's Hospital, Shenyang, Liaoning Province, 110000, People's Republic of China.
Ruiqun QiDepartment of Dermatology, the First Hospital of China Medical University, Shenyang, Liaoning Province, 110000, People's Republic of China.
Xinghua GaoDepartment of Dermatology, the First Hospital of China Medical University, Shenyang, Liaoning Province, 110000, People's Republic of China.
Lili ZhuDepartment of Dermatology, the People's Hospital of Liaoning Province, Shenyang, Liaoning Province, 110016, People's Republic of China.ORCID 0000-0002-2919-4852

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Patients with erythrodermic psoriasis (EP) complicated by end-stage renal disease (ESRD) requiring hemodialysis are extremely rare in clinical practice, and treatment options for this specific population remain highly limited. Herein we report a case of an EP patient with ESRD, in whom treatment with an interleukin-17 (IL-17) inhibitor secukinumab not only rapidly alleviated erythrodermic symptoms but also resulted in a certain degree of improvement in renal function. At the 7-month follow-up, the patient maintained skin lesion clearance with no deterioration in renal function-a finding that has not been consistently documented in previous literature. This case suggests that for patients with psoriasis complicated by kidney disease IL-17 inhibitors may serve as a potentially favorable therapeutic option.

Indexed as

end-stage renal diseaseerythrodermic psoriasisIL-17 inhibitor case report

Identifiers

PMID41180113
PMCPMC12577450

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.