Evidence map›Paper›PMID 41180091›Full record

ArticlePreventive nutrition and food science2025

Effect of Extraction pH on Hydrangenol Content in Hydrangea Tea.

Eun-Seo Beak, Ha-Rin Park, Myo-Jeong Kim

Abstract read
In one paragraph

Article in Preventive nutrition and food science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Eun-Seo BeakInstitute for Digital Antiaging Healthcare, Inje University, Gyeongnam 50834, Korea.ORCID https://orcid.org/0009-0006-7398-8349
Ha-Rin ParkInstitute for Digital Antiaging Healthcare, Inje University, Gyeongnam 50834, Korea.ORCID https://orcid.org/0009-0008-3033-9175
Myo-Jeong KimInstitute for Digital Antiaging Healthcare, Inje University, Gyeongnam 50834, Korea.ORCID https://orcid.org/0000-0002-6985-0957

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hydrangea tea is known for its unique sweet taste and contains bioactive compounds, including phyllodulcin and hydrangenol. This study aimed to investigate the factors (e.g., water type, pH, etc.) that affect the hydrangenol content in hydrangea tea and to propose methods to increase its yield. The tea extracts prepared under various conditions were analyzed using high-performance liquid chromatography (HPLC) and their hydrangenol contents were compared. Distilled water with a weakly acidic pH produced the highest hydrangenol concentration (14.36 µg/mL), which was 10.9 times higher than that obtained with mineral water at neutral pH. Further experiments using pH-adjusted water (pH 4.0-7.0) showed that the hydrangenol content increased as the pH decreased. Ascorbic acid and dried fruits were effective blending materials for decreasing the extraction pH. Among them, calamansi yielded the highest hydrangenol content (21.38 µg/mL). HPLC analysis showed that authentic hydrangenol was rapidly converted to hydrangeic acid under neutral and alkaline conditions. These results indicate that the extraction pH is an important factor for hydrangenol yield in hydrangea tea and that the yield can be improved by adding blending materials that decrease the pH into the acidic range.

Indexed as

high-performance liquid chromatographyhydrangeahydrangenoltea

Identifiers

PMID41180091
PMCPMC12567967

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.