ArticleIndustrial psychiatry journal
Association of interleukin-6 (IL-6) with suicide attempt.
Article in Industrial psychiatry journal. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Inflammation and treatment strategies for suicidal behavior.The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry · 2026Review
- Exploring the neurobiological markers of suicidal behaviors in pediatric population: a narrative review.Frontiers in pediatrics · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Suicide is a major cause of death among young adults, but few biological markers have been linked to suicidality. Interleukin-6 (IL-6) may play a role in elevating the risk of depression and suicidal tendencies. However, limited research has explored the connections between IL-6 and suicidal thoughts or actions. Aim: This study was conducted to investigate the association between IL-6 levels and suicide attempts. Materials and Methods: In this observational study, 31 patients undergoing clinical follow-up after a suicide attempt were enrolled. The Columbia Suicide Severity Rating Scale (C-SSRS) was used for assessment of suicidal behavior. IL-6 levels in patients were measured using the ELISA technique with the IL-6 Human ELISA Kit (Invitrogen, Cat. No-BMS213-2) following the manufacturer's protocols. Results: The mean level of IL-6 in the patients was 2.75 ± 6.50 (range: 0-36.6) pg/mL. Women exhibited higher IL-6 levels than men (women = 4.04 ± 8.97; men = 1.54 ± 1.86) pg/mL. IL-6 levels significantly increased with higher severity levels of suicidal ideation, with a Conclusion: This study provides evidence that elevated IL-6 levels are associated with suicide attempts, supporting its potential role as a biomarker for suicidal behavior.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.