Evidence map›Paper›PMID 41180031›Full record

ArticleSAGE open medical case reports2025

Radiation-induced cavernous malformation within a vestibular schwannoma: A case report.

Alex Z Graboyes, Alexandra E Quimby, Sabrina Heman-Ackah, Sara L Stone, Jason A Brant, Douglas C Bigelow, John Y K Lee

Abstract readCase Reports
In one paragraph

Article in SAGE open medical case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Alex Z GraboyesDepartment of Otorhinolaryngology - Head & Neck Surgery, University of Pennsylvania, Philadelphia, PA, USA.ORCID https://orcid.org/0009-0005-9412-8893
Alexandra E QuimbyDepartment of Otorhinolaryngology - Head & Neck Surgery, Dalhousie University, Halifax, NS, Canada.
Sabrina Heman-AckahDepartment of Neurosurgery, University of Pennsylvania, Philadelphia, PA, USA.
Sara L StoneDepartment of Pathology and Laboratory Medicine, University of Michigan, Ann Arbor, MI, USA.
Jason A BrantDivision of Otolaryngology - Head and Neck Surgery, Department of Surgery, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA.
Douglas C BigelowDepartment of Otorhinolaryngology - Head & Neck Surgery, University of Pennsylvania, Philadelphia, PA, USA.
John Y K LeeDepartment of Neurosurgery, University of Pennsylvania, Philadelphia, PA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cavernous malformations are a well-described complication of intracranial radiation; however, have only once previously been described within a vestibular schwannoma following radiotherapy. We report a case of a 78-year-old woman presenting with new hemifacial spasm 16-years following fractionated radiotherapy for a vestibular schwannoma, with imaging suggesting the formation of a cavernous malformation within the tumor. The patient underwent translabyrinthine resection, with final pathology confirming the diagnosis of a cavernous malformation within the vestibular schwannoma. This case highlights the need to maintain a broad differential in patients with new symptoms following radiotherapy for vestibular schwannomas, including hemifacial spasm. Cavernous malformations should be considered among potential radiation-related complications in patients with vestibular schwannoma.

Indexed as

acoustic Neuromacavernomacavernous malformationradiationradiotherapyvestibular schwannoma

Identifiers

PMID41180031
PMCPMC12576079

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.