Evidence map›Paper›PMID 41179983›Full record

ArticleJournal of arrhythmia2025

The Role of Ventricular Arrhythmias Inducibility in Arrhythmic Risk Stratification in Arrhythmogenic Right Ventricular Cardiomyopathy: A Meta-Analysis of Observational Studies.

George Bazoukis, Athanasios Saplaouras, Nikhil Pillai, Polyxeni Efthymiou, Sharen Lee, Dimitrios Sfairopoulos, Panagiotis Korantzopoulos, Gary Tse, Tong Liu, Konstantinos P Letsas

Abstract read
In one paragraph

Article in Journal of arrhythmia, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

George BazoukisDepartment of Cardiology Larnaca General Hospital, State Health Services Organization Larnaca Cyprus.ORCID https://orcid.org/0000-0003-1009-9772
Athanasios SaplaourasDepartment of Cardiology Onassis Cardiac Surgery Center Athens Greece.
Nikhil PillaiDepartment of Basic and Clinical Sciences University of Nicosia Medical School Nicosia Cyprus.
Polyxeni EfthymiouDepartment of Cardiology Nicosia General Hospital, State Health Services Organization Nicosia Cyprus.
Sharen LeeCardiac Electrophysiology Unit Cardiovascular Analytics Group Hong Kong China.
Dimitrios SfairopoulosDepartment of Cardiology University of Ioannina, Medical School Ioannina Greece.
Panagiotis KorantzopoulosDepartment of Cardiology University of Ioannina, Medical School Ioannina Greece.ORCID https://orcid.org/0000-0002-4228-3593
Gary TseTianjin Key Laboratory of Ionic-Molecular Function of Cardiovascular Disease, Department of Cardiology Tianjin Institute of Cardiology, Second Hospital of Tianjin Medical University Tianjin China.ORCID https://orcid.org/0000-0001-5510-1253
Tong LiuTianjin Key Laboratory of Ionic-Molecular Function of Cardiovascular Disease, Department of Cardiology Tianjin Institute of Cardiology, Second Hospital of Tianjin Medical University Tianjin China.
Konstantinos P LetsasDepartment of Cardiology Onassis Cardiac Surgery Center Athens Greece.ORCID https://orcid.org/0000-0001-8924-8261

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The identification of arrhythmogenic right ventricular cardiomyopathy (ARVC) patients at risk for fatal arrhythmic events is of great importance in clinical practice. Conflicting data exist regarding the role of electrophysiological study (EPS) in this setting. We aimed to examine the association of EPS inducibility with future fatal arrhythmic events in ARVC patients and its role as a risk stratification tool in the setting of primary prevention of sudden cardiac death (SCD). Methods: This meta-analysis was prepared in adherence to the Preferred Reporting Items for Systematic Review and Meta-Analyses (PRISMA) guidelines. Results: Eleven studies provided data on the association between EPS inducibility and fatal arrhythmic events and were therefore included in the quantitative analysis. EPS inducibility was significantly associated with arrhythmic events (RR: 2.15, 95% CI [1.63-2.85], Conclusions: EPS inducibility can be a valuable tool for arrhythmic risk stratification purposes in ARVC patients, especially as a component of multiparametric risk scores. More studies are needed to examine the role of multiparametric risk scores, including EPS inducibility, in identifying ARVC patients at risk for fatal arrhythmic events.

Indexed as

arrhythmogenic cardiomyopathyARVCrisk stratificationventricular arrhythmias

Identifiers

PMID41179983
PMCPMC12579493

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.