ArticlePulmonary circulation2025
The Predictive Value of Quantitative Analysis of SPECT V/Q Imaging for Postoperative Persistent/Recurrent Pulmonary Hypertension in Patients With Chronic Thromboembolic Pulmonary Hypertension After Pulmonary Endarterectomy.
Article in Pulmonary circulation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- The Utility of Extracorporeal Membrane Oxygenation in the Setting of Chronic Thromboembolic Pulmonary Hypertension.Medical sciences (Basel, Switzerland) · 2026Review
- Diagnostic Performance of Quantitative Lung Perfusion SPECT/CT for Chronic Thromboembolic Pulmonary Hypertension: A Pilot Study.Diagnostics (Basel, Switzerland) · 2026Article
- From Patient-Specific Hemodynamic Modeling to Clinical Decision-Making in Chronic Thromboembolic Pulmonary Hypertension: Opportunities and Caveats.Pulmonary circulation · 2025Article
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Authors and funding
7 authors.
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Abstract
Pulmonary endarterectomy (PEA) is a highly effective treatment for chronic thromboembolic pulmonary hypertension (CTEPH). However, persistent or recurrent pulmonary hypertension (persistent/recurrent PH) following surgery can adversely impact patients' outcomes. This study investigated the predictive value of preoperative SPECT ventilation/perfusion (V/Q) imaging for post-PEA persistent/recurrent PH. Between 2016 and 2022, CTEPH patients at our hospital underwent PEA after right heart catheterization (RHC) and SPECT V/Q imaging and were followed for 2 years. Postoperative mean pulmonary artery pressure (mPAP) ≥ 25 mmHg indicates persistent/recurrent PH. Correlations were explored between the occurrence of postoperative persistent/recurrent PH and preoperative parameters, including systolic pulmonary artery pressure (sPAP), mPAP, pulmonary vascular resistance (PVR), and parameters of the SPECT V/Q scan. Seventy-four patients were enrolled, including 52 males (71.6%). Seventeen patients (23%) developed persistent/recurrent PH within 2-80 weeks after surgery. The persistent/recurrent PH and non-persistent/recurrent PH groups exhibited statistically significant preoperative differences in preoperative mPAP, sPAP, PVR, Begic's score, and V/Q mismatched volume percentage (
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