Evidence map›Paper›PMID 41179914›Full record

ArticlePulmonary circulation2025

m6A Methylation-Modified hsa_circ_0044226 Attenuates Pulmonary Fibrosis by Suppressing Ferroptosis.

Fei Qi, Liwei Liu, Cheng Peng, Xin Gao, Shanchen Wei, Ming Zhang, Qian Zhou

Abstract read
In one paragraph

Article in Pulmonary circulation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Fei QiSchool of Clinical Medicine Anhui Institute of Medicine Hefei City Anhui Province People's Republic of China.ORCID https://orcid.org/0009-0007-5426-1766
Liwei LiuCollege of Medical Technology Anhui Institute of Medicine Hefei City Anhui Province People's Republic of China.
Cheng PengDepartment of Thoracic Surgery The First Affiliated Hospital of Anhui University of Chinese Medicine Hefei City People's Republic of China.
Xin GaoSchool of Clinical Medicine Anhui Institute of Medicine Hefei City Anhui Province People's Republic of China.
Shanchen WeiDepartment of Pulmonary and Critical Care Medical China-Japan Friendship Hospital Beijing City People's Republic of China.
Ming ZhangSchool of Clinical Medicine Anhui Institute of Medicine Hefei City Anhui Province People's Republic of China.
Qian ZhouSchool of Clinical Medicine Anhui Institute of Medicine Hefei City Anhui Province People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Idiopathic Pulmonary fibrosis (IPF) is a debilitating lung condition marked by chronic progression and reduced lung function. This study aimed to explore the functional role and regulatory mechanism of circular RNA circ_0044226 in the pathogenesis of pulmonary fibrosis. The expression of circ_0044226 was analyzed in peripheral blood and TGF-β1-stimulated RLE-6TN cells using qRT-PCR. The cellular location of circ_0044226 was analyzed using FISH. The expression levels of circ_0044226 and METTL3 were evaluated in cells and clinical samples. Protein levels of GPX4 and FTH1 were examined using Western blot, while the levels of MDA, Fe

Indexed as

circ_0044226ferroptosism6A modificationMETTL3pulmonary fibrosis

Identifiers

PMID41179914
PMCPMC12576025

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.