ArticleFrontiers in medicine2025
Ultrasound characterization of superficial lymph nodes in HIV patients with lymphadenopathy.
Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background and aims: HIV infection leads to immune deficiency and opportunistic infections, often presenting with lymphadenopathy. This study aims to characterize superficial lymph nodes in HIV patients using ultrasound and correlate these findings with T cell subset data to differentiate benign from malignant conditions. Methods: A retrospective observational study was conducted on 149 HIV patients with lymphadenopathy from March 2016 to March 2024. Ultrasound examinations were performed, and pathological results were obtained through biopsy. Statistical analysis included univariate and multivariate logistic regression to identify predictors of malignancy. Results: Ultrasound findings showed that malignant lymph nodes were larger, with a lower L/S ratio, absent hilum, and hypoechoic appearance. Immunological data revealed higher lymphocyte counts, T cell counts, and CD4 Conclusion: Ultrasound combined with T cell subset analysis may assists benign and malignant lymphadenopathy in HIV patients. The CD4
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