ArticleFrontiers in medicine2025
Clinical trial effects of acupuncture combined with different general anesthesia on postoperative nausea and vomiting and early recovery after thyroidectomy with intra-operative neuromonitoring: a randomized controlled trial.
Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Efficacy of multimodal symptom management strategies for chemotherapy-induced nausea and vomiting in gynecologic cancer: a meta-analysis.American journal of cancer research · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Intraoperative neuromonitoring (IONM) is widely used to preserve recurrent laryngeal nerve (RLN) function during thyroid surgery. However, patients undergoing thyroidectomy with IONM may experience a higher incidence of postoperative nausea and vomiting (PONV) and poorer recovery quality. Both acupuncture and propofol anesthesia have been investigated as potential strategies to prevent PONV, but clinical evidence on their combined use in thyroidectomy is limited. This study aimed to evaluate the effects of propofol-based anesthesia combined with postoperative acupuncture on PONV and early recovery within 24 h after thyroidectomy with IONM. Methods: A total of 135 adult patients were randomly assigned to one of four groups: sevoflurane with sham acupuncture ( Results: Compared with sevoflurane, propofol anesthesia significantly reduced PONV severity (OR = 0.313; 95% CI, 0.123-0.797; Conclusion: Both propofol anesthesia and postoperative acupuncture independently reduced the incidence and severity of PONV after thyroidectomy with IONM. No synergistic effect was observed, possibly due to mechanistic differences or the limited intensity of the acupuncture protocol. Further research is warranted to optimize acupuncture parameters and clarify the clinical utility of combined approaches across broader surgical settings. Clinical trial registration: The clinical trial was registered in the Chinese Clinical Trial Registry under the identifier ChiCTR2400082127.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.