Evidence map›Paper›PMID 41179861›Full record

ArticleFrontiers in medicine2025

Hemoglobin and clinical outcomes of in-hospital patients with severe acute exacerbation of chronic obstructive pulmonary disease: a multicenter cohort study.

Suji Wu, Qun Yi, Yuanming Luo, Hailong Wei, Huiqing Ge, Huiguo Liu, Xianhua Li, Jianchu Zhang, Pinhua Pan, Mengqiu Yi and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Suji WuDepartment of Respiratory and Critical Care Medicine, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Qun YiDepartment of Respiratory and Critical Care Medicine, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Yuanming LuoState Key Laboratory of Respiratory Disease, Guangzhou Medical University, Guangzhou, Guangdong, China.
Hailong WeiDepartment of Respiratory and Critical Care Medicine, People's Hospital of Leshan, Leshan, Sichuan, China.
Huiqing GeDepartment of Respiratory and Critical Care Medicine, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.
Huiguo LiuDepartment of Respiratory and Critical Care Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Xianhua LiDepartment of Respiratory and Critical Care Medicine, The First People's Hospital of Neijiang City, Neijiang, Sichuan, China.
Jianchu ZhangDepartment of Respiratory and Critical Care Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Pinhua PanDepartment of Respiratory and Critical Care Medicine, Xiangya Hospital, Central South University, Changsha, Hunan, China.
Mengqiu YiDepartment of Emergency, The First People's Hospital of Jiujiang, Jiujiang, Jiangxi, China.
Lina ChengDepartment of Emergency, The First People's Hospital of Jiujiang, Jiujiang, Jiangxi, China.
Hui ZhouDepartment of Respiratory and Critical Care Medicine, The Affiliated Hospital of Chengdu University, Chengdu, China.
Yongjiang TangDepartment of Respiratory and Critical Care Medicine, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Haixia ZhouDepartment of Respiratory and Critical Care Medicine, West China Hospital, Sichuan University, Chengdu, Sichuan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Hemoglobin is one of the most common laboratory tests for hospitalized patients, and both anemia and polycythemia are common comorbidities in severe acute exacerbation of chronic obstructive pulmonary disease (AECOPD). However, limited evidence focuses on the predictive value of anemia or polycythemia for in-hospital adverse outcomes of severe AECOPD. Methods: The patients hospitalized for severe AECOPD were prospectively enrolled from 10 medical centers in China. They were categorized into three groups: anemia, normal, and polycythemia, based on their hemoglobin levels on-admission. The adverse outcomes which included all-cause in-hospital mortality, invasive ventilation, and intensive care unit (ICU) admission. Results: A total of 9,660 AECOPD inpatients were included. The cohort identified a significant association between anemia and adverse outcomes when compared to the normal group (5.20% vs. 2.80%, Conclusion: While there is no effect of polycythemia on adverse outcomes in severe AECOPD inpatients, anemia on-admission, particularly <9 g/dL, is associated with a heightened risk of adverse outcomes, which may serve as an effective biomarker of poor prognosis among inpatients with severe AECOPD.

Indexed as

acute exacerbationadverse outcomeanemiachronic obstructive pulmonary diseasepolycythemia

Identifiers

PMID41179861
PMCPMC12571645

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.