Evidence map›Paper›PMID 41179651›Full record

Trial reportPain research & management2025

Multimodal Active Physiotherapy Versus Multimodal Passive Physiotherapy for Chronic Nonspecific Neck Pain: A Randomized Controlled Trial on Dual Outcomes of Physical and Mental Health.

Jialin Wang, Shuyi Nie, Ruirui Wang, Yuwei He, Meng Li, Xinwen Cui, Zhoupeng Lu, Hui Zou, Yiping Zhao, Jianfa Xu and 1 more

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Pain research & management, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jialin WangSports Rehabilitation Research Center, China Institute of Sport Science, Beijing, China.ORCID https://orcid.org/0000-0002-7841-8146
Shuyi NieCollege of Sports Medicine and Physical Therapy, Beijing Sport University, Beijing, China.ORCID https://orcid.org/0009-0003-5910-1623
Ruirui WangCollege of Sports Medicine and Physical Therapy, Beijing Sport University, Beijing, China.ORCID https://orcid.org/0000-0002-5440-9405
Yuwei HeCollege of Sports Medicine and Physical Therapy, Beijing Sport University, Beijing, China.ORCID https://orcid.org/0009-0001-5880-025X
Meng LiCollege of Sports Medicine and Physical Therapy, Beijing Sport University, Beijing, China.ORCID https://orcid.org/0009-0007-3258-3406
Xinwen CuiSports Rehabilitation Research Center, China Institute of Sport Science, Beijing, China.ORCID https://orcid.org/0000-0001-5381-4938
Zhoupeng LuCollege of Sports Medicine and Physical Therapy, Beijing Sport University, Beijing, China.ORCID https://orcid.org/0009-0007-7661-7970
Hui ZouCollege of Sports Medicine and Physical Therapy, Beijing Sport University, Beijing, China.ORCID https://orcid.org/0009-0004-5488-9068
Yiping ZhaoCollege of Sports Medicine and Physical Therapy, Beijing Sport University, Beijing, China.ORCID https://orcid.org/0009-0002-9276-0826
Jianfa XuSports Rehabilitation Research Center, China Institute of Sport Science, Beijing, China.ORCID https://orcid.org/0009-0003-4136-5743
Peng ZhaoSports Rehabilitation Research Center, China Institute of Sport Science, Beijing, China.ORCID https://orcid.org/0000-0002-1516-4062

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Active physiotherapy utilizes patient-centered, sensorimotor-integrated interventions to modulate central nervous system function. This randomized controlled trial (RCT) compared the efficacy of multimodal active physiotherapy (MAP) versus multimodal passive physiotherapy (MPP) in improving physical and mental health in chronic nonspecific neck pain (CNNP) patients. Methods: This single-blind, stratified parallel-group RCT included 54 patients with CNNP. Participants were randomly assigned to the MAP or MPP group, both receiving 16 treatment sessions (60 min/session) over 8 weeks. Primary outcomes were pain intensity (Numeric Pain Rating Scale) and emotional status (Hospital Anxiety and Depression Scale). Secondary outcomes included patient-perceived change, pain modulation, insomnia symptoms, kinesiophobia, neck function, and mental health-related quality of life (QoL). Intention-to-treat analyses were performed. Results: Postintervention, there were no significant group-time interactions in the primary outcomes (pain intensity, anxiety, and depression; all Conclusion: In patients with CNNP, MAP and MPP result in comparable improvements in pain and emotional status; however, MAP demonstrates superior benefits relative to MPP in pain modulation, movement-related fear, and mental health-related QoL. Trial Registration: Chinese Registry of Clinical Trials: ChiCTR2500104619.

Indexed as

Chronic PainMental HealthNeck PainPhysical Therapy ModalitiesAdultCombined Modality TherapyFemaleHumansMaleMiddle AgedPain MeasurementQuality of LifeSingle-Blind MethodTreatment Outcomechronic nonspecific neck painmental healthmultimodal active physiotherapyphysical health

Identifiers

PMID41179651
PMCPMC12575025

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.