ArticleAfrican health sciences2025
Seroprevalence of anti-SARS-CoV-2 IgG antibodies among vaccinated healthcare workers in Bamako, Mali.
Article in African health sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Work in progress on infections, reproductive sexual health, education and non-communicable diseases.African health sciences · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
19 authors.
Funding
Abstract
Introduction: Like many other countries, Mali, a West African country, has encountered various obstacles in the fight against the transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Despite resource constraints, however, the country implemented containment strategies. Therefore, in early 2021, Mali initiated a vaccination campaign as a tangible defense against COVID-19, prioritizing the administration of the first vaccine doses to healthcare personnel. Consequently, we found assessing anti-SARS-CoV-2 IgG antibody levels important to gauge the efficacy of vaccines administered to frontline healthcare workers in Bamako, Mali. Methods: The study enrolled 172 vaccinated front-line healthcare workers from referral hospitals in Bamako, Mali, between March and June 2022. Serum samples were subjected to enzyme-linked immunosorbent assay (ELISA) to assess the levels of anti-SARS-CoV-2 IgG antibodies. Prevaccination serum samples served as controls. Chi-square and Mann-Whitney tests were used to compare proportions and means. Results: Among the 172 participants, 98.2% had high levels of anti-SARS-CoV-2 spike protein antibodies; only 1.6% (n=2) were seronegative. The majority, 62.2% (n=107), received a two-dose vaccination schedule, and the Astra Zeneca® vaccine was the most widely used (52.3%). The average level of postvaccine antibodies was significantly greater in participants who received two doses of vaccine than in those who received one dose (33.7 index vs. 29.1 index; p=0.02). Conclusions: Most healthcare workers exhibited favorable vaccine responses, as indicated by their positive reactivity to anti-SARS-CoV-2 IgG spike proteins. The nature and dosage of the vaccines influenced the antibody response, with a notable advantage observed for individuals who received a two-dose regimen. These findings underscore the importance of continuous research and evaluation to understand and enhance vaccine effectiveness.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.