Evidence map›Paper›PMID 41179373›Full record

ArticleSaudi journal of ophthalmology : official journal of the Saudi Ophthalmological Society

Multidisciplinary management of nasal and lacrimal drainage disorders in ectrodactyly-ectodermal dysplasia-clefting syndrome.

Nandini Bothra, Lisa Y Lin, Benjamin S Bleier, Suzanne K Freitag

Abstract readCase Reports
In one paragraph

Article in Saudi journal of ophthalmology : official journal of the Saudi Ophthalmological Society. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Nandini BothraGovindram Seksaria Institute of Dacryology, L.V Prasad Eye Institute, Hyderabad, Telengana, India.
Lisa Y LinOphthalmic Plastic Surgery Service, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, MA, USA.
Benjamin S BleierDepartment of Otolaryngology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, MA, USA.
Suzanne K FreitagOphthalmic Plastic Surgery Service, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, MA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ectrodactyly-ectodermal dysplasia-clefting syndrome (EECS) and its association with lacrimal drainage disorders are well known. EECS has p63 gene mutations which affect the ectodermal, orofacial, and limb development along with developmental delay affecting the entire body. Complex lacrimal drainage anomalies typically require endoscopic guidance through the nose for successful outcomes. p63 gene mutations affect the nasal structural development, making the surgical access as well as the outcomes in complex lacrimal drainage disorders difficult to predict and achieve. The present case describes a multidisciplinary approach of the oculoplastic and rhinology services in managing a complex lacrimal drainage disorder.

Indexed as

Complex congenital nasolacrimal duct obstructiondacryocystorhinostomyectrodactyly–ectodermal dysplasia–clefting syndromelacrimalnasal developmental disordersyndromic congenital nasolacrimal duct obstruction

Identifiers

PMID41179373
PMCPMC12578411

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.