ArticleCancer diagnosis & prognosis
Impact of Surgical Refusal on Overall Survival in Patients With Rectal Cancer.
Article in Cancer diagnosis & prognosis. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
15 authors.
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Abstract
Background/Aim: While surgery is a major component of treatment for managing rectal cancer, some individuals opt against it, potentially affecting their chances of survival. This study investigated the clinical and demographic elements linked to the decision to refuse surgery and assessed the potential impact of this decision on overall survival (OS). Patients and Methods: We conducted a retrospective cohort study using the U.S. National Cancer Database to analyze factors linked to surgery refusal in patients with rectal cancer. Clinical, demographic and treatment characteristics were compared using Pearson chi-square and Wilcoxon rank-sum tests. Results: Among the 115,066 patients with rectal cancer assessed for surgery, 2,675 individuals (2.3%) declined the procedure. Those who opted out were generally older, with a mean age of 71.9 years, exhibited a higher prevalence of comorbid conditions, and were from racial minority groups or groups with lower socioeconomic status ( Conclusion: Patients with rectal cancer may decline surgical treatment due to factors such as older age, frailty, and socioeconomic challenges. Addressing these obstacles may increase treatment acceptance and potentially lead to improved survival rates.
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