Evidence map›Paper›PMID 41179274›Full record

ArticleJCEM case reports2025

Acute Deep Vein Thrombosis in the Setting of Tirzepatide Use: A Case Highlighting Emerging Concerns.

Kunal Sonavane, Gautam Agrawal, Bhawna Agarwal, Saketh Parsi, Hari Krishna Choudary Ponnam, Pallavi Shirsat

Abstract readCase Reports
In one paragraph

Article in JCEM case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Kunal SonavaneWillis Knighton Health, Bossier City, LA 71111, USA.ORCID https://orcid.org/0009-0005-1402-4876
Gautam AgrawalIndependence Health System, Greensburg, PA 15601, USA.
Bhawna AgarwalUniversity of Pittsburgh Medical Center, McKeesport, PA 15132, USA.
Saketh ParsiAscension Seton Medical Center Austin, Austin, TX 78705, USA.
Hari Krishna Choudary PonnamSumma Health System, Akron, OH 44304, USA.
Pallavi ShirsatMinden Medical Center, Minden, LA 71055, USA.ORCID https://orcid.org/0000-0003-4969-3488

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tirzepatide, a dual glucose-dependent insulinotropic polypeptide and glucagon-like peptide 1 agonist, is gaining popularity for its weight reduction, improved glycemic control, and cardiorenal benefits. While it is generally well tolerated, thrombotic events have not been commonly reported. We report a case of a woman who developed an unprovoked deep vein thrombosis within months of starting tirzepatide. An extensive hypercoagulability workup was negative. Her symptoms improved with anticoagulation and discontinuation of tirzepatide. This case highlights a potential risk of thromboembolic events associated with tirzepatide. Clinicians need to be vigilant and exercise extreme caution as the emerging adverse event profile of this novel medication unfolds.

Indexed as

deep vein thrombosisDVTGLP-1 agoniststirzepatide

Identifiers

PMID41179274
PMCPMC12574538

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.