ArticleBJR case reports2025
Severe cytomegalovirus encephalitis in an immunocompetent man: a case report.
Article in BJR case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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6 authors.
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Abstract
Cytomegalovirus (CMV) is a viral infection that is generally considered benign in immunocompetent patients; however, it can be life-threatening in immunocompromised patients. We present the case of a 46-year-old patient with severe primary CMV encephalitis. The patient presented to the hospital emergency department with impaired alertness and speech. A brain scan and initial lumbar puncture (LP) were normal. However, the patient's state of consciousness deteriorated rapidly with the onset of seizures, prompting a brain MRI scan, which revealed lesions suggestive of encephalitis. Polymerase Chain Reaction (PCR) detection of cytomegalovirus was confirmed on a second lumbar puncture. Following the confirmation of the diagnosis, the patient was commenced on appropriate antiviral treatment, which resulted in a favourable outcome. Our aim is to report on the clinical manifestations and the contribution of imaging to the diagnosis of CMV encephalitis in immunocompetent persons.
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