A Direct Oxidation of Diarylalkynes Containing Quinazolinones to 1,2-Diketone Derivatives with PIFA and PhSeSePh.

Yujie Chen, Dong Deng, Haitao Chen, Yuehua Zhang, Junying Ge, Jun Chen, Junyue Lin

Abstract read

In one paragraph

Article in ACS omega, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yujie ChenKey Laboratory of Jiangxi University for Applied Chemistry and Chemical Biology, Yichun University, Yichun 336000, China.

Dong DengKey Laboratory of Jiangxi University for Applied Chemistry and Chemical Biology, Yichun University, Yichun 336000, China.

Haitao ChenKey Laboratory of Jiangxi University for Applied Chemistry and Chemical Biology, Yichun University, Yichun 336000, China.

Yuehua ZhangCollege of Physical Education, Yichun University, Yichun 336000, China.

Junying GeKey Laboratory of Jiangxi University for Applied Chemistry and Chemical Biology, Yichun University, Yichun 336000, China.ORCID https://orcid.org/0009-0005-2376-0154

Jun ChenKey Laboratory of Jiangxi University for Applied Chemistry and Chemical Biology, Yichun University, Yichun 336000, China.

Junyue LinCollege of Chemistry & Chemical Engineering, Jinggangshan University, Jian 343009, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A simple and effective (bis-(trifluoroacetoxy)-iodo) benzene (PIFA) and organoselenium comediated aerobic oxidative reaction of 3-(2-(ethynyl)-aryl) quinazolinones for the synthesis of 1-(2-(4-oxoquinazolin-3-(4H)-yl) phenyl)-2-phenylethane-1,2-diones has been developed. The regioselective reaction proceeds smoothly under metal-free and catalyst-free conditions and provides 1,2-diketones with high chemoselectivity. The wide substrate scope can be applied by experimental studies to afford 1,2-diketones in good yields. A possible pathway for this transformation is proposed on the basis of the preliminary mechanistic investigation, which indicated a radical process.

Identifiers

PMID41179228

DOI10.1021/acsomega.5c06643

PMCPMC12573040

What OpenQuestion holds

Textmetadata

LicenceCC BY-NC-ND

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.